268R-1

IgD (EP173) Rabbit Monoclonal Primary Antibody

• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100; 500
• 結合体: unconjugated
• 抗体製品の状態: culture supernatant
• 抗体製品タイプ: primary antibodies
• クローン: EP173, monoclonal
• 詳細: (For In Vitro Diagnostic Use in Select Regions (See Chart))
• フォーム: buffered aqueous solution
• 化学種の反応性: human
• 包装: bottle of 1.0 mL predilute (268R-17); bottle of 7.0 mL predilute (268R-18); vial of 0.1 mL concentrate (268R-14); vial of 0.5 mL concentrate (268R-15); vial of 1.0 mL concentrate (268R-16)
• メーカー／製品名: Cell Marque^™
• テクニック: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
• アイソタイプ: IgG
• 輸送温度: wet ice
• 保管温度: 2-8°C

詳細

詳細

The monoclonal antibody against IgD reacts with immunoglobin D delta chains. In tonsil and lymph node, immunohistochemical staining for IgD immunoglobulin heavy chain is usually used to highlight the tonsil and nodal architecture since the IgD antibody stains mantle zone cells in secondary follicles and mantle cells in primary follicles.¹ It has been reported that IgD can be detected in the surface/cytoplasm of neoplastic cells of common small B lymphoid cell lymphomas, such as small lymphocytic lymphoma, mantle cell lymphoma, marginal zone lymphoma (especially splenic marginal zone lymphoma), and follicular lymphoma.^1-2 IgD expression in L & P cells of nodular lymphocyte predominant Hodkin lymphoma has been seen in subsets of cases (27% to 71.4%).^1-3 The IgD positive L & P cells are usually located in the extrafollicular area with a relatively T-cell-rich background^1,3 IgD expression is rarely seen in T-cell rich B-cell lymphoma. Studies have demonstrated that Reed-Sternberg cells of classic Hodgkin lymphoma were negative for IgD^1,3 IgD multiple myeloma is a rare bone marrow plasma cell dyscrasia and can be identified by the IgD antibody, especially when a dry tap is encountered.⁴

品質

IVD

IVD

IVD

RUO

関連事項

IgD Positive Control Slides, Product No. 268S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

物理的形状

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

調製ノート

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

その他情報

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法的情報

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable