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由来生物
rabbit
品質水準
100
500
結合体
unconjugated
抗体製品の状態
culture supernatant
抗体製品タイプ
primary antibodies
クローン
EP267, monoclonal
詳細
(For In Vitro Diagnostic Use in Select Regions (See Chart))
フォーム
buffered aqueous solution
交差性
human
包装
bottle of 1.0 mL predilute (208R-17)
bottle of 7.0 mL predilute (208R-18)
vial of 0.1 mL concentrate (208R-14)
vial of 0.5 mL concentrate (208R-15)
vial of 1.0 mL concentrate (208R-16)
メーカー/製品名
Cell Marque®
テクニック
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
アイソタイプ
IgG
輸送温度
wet ice
保管温度
2-8°C
遺伝子情報
mouse ... Gh(14599)
詳細
Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Human growth hormone contains 191 amino acid residues with two disulfide bridges. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).1-3 It reacts with GH-producing cells. Growth hormone receptors have been found in various non-pituitary cells, including that from hepatocellular carcinoma and various benign and malignant cutaneous lesions.4-6
品質
![]() IVD | ![]() IVD | ![]() IVD | ![]() RUO |
関連事項
GH Positive Control Slides, Product No. 208S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
物理的形状
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.
調製ノート
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
その他情報
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法的情報
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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最新バージョンのいずれかを選択してください:
A Matsuno et al.
Pathology, research and practice, 197(1), 13-20 (2001-02-24)
To characterize the morphological and functional aspects of silent somatotroph adenomas with paradoxical responses of GH in TRH or GnRH provocation tests, which are considered to be a useful strategy for endocrinological identification of silent somatotroph adenomas, we examined three
L K Chopin et al.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 12(2), 126-136 (2002-08-15)
Prostate cancer is a significant cause of morbidity and mortality in Western males. While it is known that androgens play a central role in prostate cancer development and progression, other hormones and growth factors are also involved in prostate growth.
T García-Caballero et al.
Endocrine, 12(3), 265-271 (2000-08-30)
The liver is an essential target tissue for growth hormone (GH) and prolactin (PRL). The aim of this study was to determine the in situ expression of growth hormone receptor (GHR) and prolactin receptor (PRLR) in hepatocellular carcinomas and to
K S G Cunha et al.
Journal of clinical pathology, 56(10), 758-763 (2003-09-30)
The hallmark of neurofibromatosis type 1 (NF1) is the development of multiple neurofibromas. Solitary neurofibroma may occur in an individual who does not have NF1, but multiple neurofibromas tend to develop only in those with NF1. It has been suggested
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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