10937

N-テトラデカノイル-DL-ホモセリンラクトン

≥97.0% (HPLC)

• 別名: N-ミリストイル-DL-ホモセリンラクトン
• 実験式（ヒル表記法）: C₁₈H₃₃NO₃
• CAS番号: 98206-80-5
• 分子量: 311.46
• Beilstein: 1649579
• MDL番号: MFCD01862913
• UNSPSCコード: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 57646860
• NACRES: NA.26

特性

• product name: N-テトラデカノイル-DL-ホモセリンラクトン, ≥97.0% (HPLC)
• 品質水準: 100
• アッセイ: ≥97.0% (HPLC)
• 形状: powder
• 色: white to slightly yellow
• アプリケーション: cell analysis
• 保管温度: 2-8°C
• SMILES記法: CCCCCCCCCCCCCC(=O)NC1CCOC1=O
• InChI: 1S/C18H33NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-17(20)19-16-14-15-22-18(16)21/h16H,2-15H2,1H3,(H,19,20)
• InChI Key: ZQAYHOXXVBVXPZ-UHFFFAOYSA-N

詳細

アプリケーション

通常はホモセリンラクトンを産生できないChromobacterium violaceumにおいてビオラセインの発現を誘導します。

生物化学的／生理学的作用

N-Tetradecanoyl-DL-homoserine lactone (C14-HSL) is among a group of homoserine lactones that includes; N-Heptanoyl-DL-homoserine lactone (C7HSL), N-octanoyl-homoserine lactone (N-C8-HSL), N-Decanoyl-DL-homoserine lactone (N-C10-HSL), N-Dodecanoyl-DL-homoserine lactone (C12-HSL), N-(3-oxodecanoyl) homoserine-L-lactone (3-oxo-C10 HSL), N-(3-oxododecanoyl)homoserine-L-lactone (3-oxo-C12-HSL), N-(3-Oxotetradecanoyl)-L-homoserine lactone (3-oxo-C14-HSL, N-(3-hydroxydecanoyl)-L-homoserine lactone, and N-(3-hydroxyoctanoyl)-L-homoserine lactone involved in the processes of bacterial quorum sensing. These N-acyl-homoserine lactones are used to study the processes and mechanisms of bacterial quorum sensing.

N-Tetradecanoyl-DL-homoserine lactone is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) regulate gene expression in gram-negative bacteria, such as Echerichia and Salmonella are involved in quorum sensing, cell to cell communication among bacteria. Some AHLs are potent chemoattractants for human immune cells such as neutrophils.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)