PHR2552

パロノセトロン 塩酸塩

• 別名: (3aS)-2-[(3S)-キヌクリジン-3-イル]-2,3,3a,4,5,6-ｊヘキサヒドロ-1H-ベンゾ[de]イソキノリン-1-オン 塩酸塩, (3aS)-2-[(3S)-1-アザビシクロ[2.2.2]オクト-3-イル]-2,3,3a,4,5,6-ヘキサヒドロ-1H-ベンゾ[de]イソキノリン-1-オン塩酸塩(1:1), RS 25259-197
• 実験式（ヒル表記法）: C₁₉H₂₄N₂O · HCl
• CAS番号: 135729-62-3
• 分子量: 332.87
• MDL番号: MFCD00939524
• UNSPSCコード: 41116107
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to USP 1492200
• 詳細: Pharmaceutical Secondary Standard; Certified Reference Material
• APIファミリー: palonosetron
• フォーム: powder
• CofA: current certificate can be downloaded
• 包装: pkg of 200 mg
• アプリケーション: pharmaceutical small molecule
• 保管温度: 2-30°C
• SMILES記法: O=C1N([C@H]2C3CCN(CC3)C2)C[C@]4([H])C5=C1C=CC=C5CCC4.[H]Cl
• InChI: 1S/C19H24N2O.ClH/c22-19-16-6-2-4-14-3-1-5-15(18(14)16)11-21(19)17-12-20-9-7-13(17)8-10-20;/h2,4,6,13,15,17H,1,3,5,7-12H2;1H/t15-,17-;/m1./s1
• InChI Key: OLDRWYVIKMSFFB-SSPJITILSA-N

詳細

詳細

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

アプリケーション

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生物化学的／生理学的作用

パロノセトロンは、化学療法による悪心・嘔吐（CINV）の予防および治療に使用される、強力な選択的5-HT3受容体アンタゴニスト（Aloxi）です。

パロノセトロンは、強力な選択的5-HT3受容体アンタゴニストです。

アナリシスノート

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

脚注

To see an example of a Certificate of Analysis for this material enter LRAC5931 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302
• 注意書き: P264 - P270 - P301 + P312 - P501
• 危険有害性の分類: Acute Tox. 4 Oral
• 保管分類コード: 13 - Non Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable