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安全性情報

RMNPMAG-83K

Millipore

MILLIPLEX® Rat/Mouse Neuropeptide Magnetic Bead Panel - Neuroscience Multiplex Assay

The analytes available for this multiplex kit are: α-MSH, β-Endorphin, Neurotensin, Oxytocin, Substance P.

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About This Item

UNSPSCコード:
12161503
eCl@ss:
32161000
NACRES:
NA.84

品質水準

200

化学種の反応性

mouse, rat

メーカー／製品名

Milliplex®

assay range

accuracy: 107-135%
(Rat)
standard curve range: 14-100,000 pg/mL
(Oxytocin)
standard curve range: 27-20,000 pg/mL
(Neurotensin)
standard curve range: 3-2,000 pg/mL
(Substance P)
standard curve range: 41-30,000 pg/mL
(α-MSH)
standard curve range: 69-50,000 pg/mL
(β-Endorphine)

テクニック

multiplexing: suitable

検出方法

fluorometric (Luminex xMAP)

輸送温度

wet ice

詳細

The MILLIPLEX® Rat/Mouse Neuropeptide Bead Panel, containing 5 biomarkers. This kit may be used for the analysis of all or any combination of the above analytes in tissue/cell lysate/culture supernatant samples and cerebrospinal fluid (CSF). Serum or plasma samples may also be used, and will need to be extracted, however we do not recommend using the panel for serum and plasma Substance P. The kit contains enough material to analyze 38 samples in duplicate, including the standard curve and two quality controls.

An important note about this panel is that the samples may be extracted using either the acetonitrile precipitation technique or the Waters 96-well HLB extraction plate. Please refer to the protocol for more information on both methods. The necessary components to perform the extractions are not included with the kit.

The central nervous system is a complex environment consisting of billions of neurons as well as glial support cells. These neurons use many different chemical signals to communicate information, including neurotransmitters, cannabinoids, peptides, and gases such as nitric oxide. Neuropeptides are secreted primarily from the central and peripheral nervous systems, exerting a broad spectrum of biological functions that includes the regulation of metabolism, reproduction, and immunity.

Panel Type: Neuroscience

アプリケーション

  • Analytes: α-MSH, β-Endorphin, Neurotensin, Oxytocin, Substance P.
  • Recommended Sample type: serum, plasma, CSF, and tissue culture
  • Recommended Sample dilution: This assay requires 50 μL extracted serum or plasma sample per well or 50 μL neat CSF or culture media per well
  • Assay Run Time: Overnight
  • NOTE: this is a competitive assay.

特徴および利点

Design your multiplex kit by choosing available analytes within this panel.

その他情報

Sensitivity: Refer to kit protocol for sensitivities of individual biomarkers.

法的情報

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

ピクトグラム

Skull and crossbonesEnvironment
GHS06,GHS09

シグナルワード

Danger

危険有害性情報

H302 + H332,H311,H317,H411

危険有害性の分類

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1

保管分類コード

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

RMNPMAG-83K-05:
RMNPMAG-83K-02:
RMNPMAG-83K-04:
RMNPMAG-83K-01:
RMNPMAG-83K:
RMNPMAG-83K-06:
RMNPMAG-83K-03:

試験成績書（COA）

製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

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文書ライブラリにアクセスする

Willem J van den Brink et al.
The AAPS journal, 19(1), 274-285 (2016-10-28)
To reveal unknown and potentially important mechanisms of drug action, multi-biomarker discovery approaches are increasingly used. Time-course relationships between drug action and multi-biomarker profiles, however, are typically missing, while such relationships will provide increased insight in the underlying body processes.
Jen-Yin Goh et al.
Brain, behavior, and immunity, 89, 100-117 (2020-06-03)
Many psychiatric illnesses have a multifactorial etiology involving genetic and environmental risk factors that trigger persistent neurodevelopmental impairments. Several risk factors have been individually replicated in rodents, to understand disease mechanisms and evaluate novel treatments, particularly for poorly-managed negative and
Jorge Moreno-Fernández et al.
Nutrients, 11(10) (2019-10-09)
Iron deficiency anemia (IDA) is one of the most prevalent nutritional deficiencies worldwide. Iron plays critical roles in nervous system development and cognition. Despite the known detrimental consequences of IDA on cognition, available studies do not provide molecular mechanisms elucidating
Weiling Yin et al.
Neurobiology of aging, 83, 1-10 (2019-10-05)
The perimenopausal transition at middle age is often associated with hot flashes and sleep disruptions, metabolic changes, and other symptoms. Whereas the mechanisms for these processes are incompletely understood, both aging (AG) and a loss of ovarian estrogens play contributing

関連コンテンツ

獣医学および動物衛生研究におけるマルチプレックス | MILLIPLEX®アッセイ

実験動物、コンパニオンアニマル、農業用動物の研究におけるバイオマーカー検出マルチプレックス・イムノアッセイの利点と、獣医学および動物衛生研究のためのMILLIPLEX®マルチプレックスアッセイについて説明します。

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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