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Merck

MAP2MAG-76K

Millipore

MILLIPLEX® Mouse Acute Phase Magnetic Bead Panel 2 - Cardiovascular Disease Multiplex Assay

The analytes available for this multiplex kit are: Adipsin, Alpha-1 Acid Glycoprotein (AGP), Alpha-2 Macroglobulin (A2M), C-Reactive Protein, Haptoglobin, SAP.

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About This Item

UNSPSCコード:
12161503
eCl@ss:
32161000
NACRES:
NA.84

品質水準

化学種の反応性

mouse

メーカー/製品名

Milliplex®

assay range

accuracy: 99.2-128.2%
sensitivity: 0.001-7.495 ng/mL
standard curve range: 0.001-0.5 ng/mL
(AGP)

standard curve range: 0.005-4.0 ng/mL
(Adipsin)

standard curve range: 0.014-10 ng/mL
(CRP)

standard curve range: 0.549-400 ng/mL
(Haptoglobin)

standard curve range: 13.717-10,000 ng/mL
(SAP)

standard curve range: 6.858-5000 ng/mL
(A2M)

inter-assay cv: <15%
intra-assay cv: <10%

テクニック

multiplexing: suitable

検出方法

fluorometric (Luminex xMAP)

輸送温度

wet ice

詳細

Acute phase proteins are a class of proteins whose circulating concentrations increase (positive acute phase proteins) or decrease (negative acute phase proteins) in response to inflammation. This response is called the acute phase reaction or acute phase response. In recent years several new acute phase proteins have been identified, some of which are secreted from adipose tissue.

MILLIPLEX® Mouse Acute Phase Magnetic Bead Panel 2 is a 6-plex kit to be used for the simultaneous quantification of any or all of the following analytes in mouse serum or plasma samples, mouse tissue extract, or cell/tissue culture supernatant samples: Adipsin (Complement Factor D), Alpha-1 Acid Glycoprotein (AGP), C-Reactive Protein (CRP), Haptoglobin (HPTGN), Alpha-2 Macroglobulin (A2M) and Serum Amyloid Protein/Pentraxin-2 (SAP). This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Cardiovascular

特異性

Cross Reactivty
Antibody pairs in the panel are specific and demonstrate no cross-reactivity (<0.1%) with
other analytes in the panel.

アプリケーション

  • Analytes: α-1, Acid Glycoprotein (AGP), α-2 Macroglobulin (A2M), Adipsin (Factor D), C-Reactive Protein (CRP), Haptoglobin, Serum Amyloid P (SAP)
  • Recommended Sample Type: Mouse serum, plasma or cell/tissue culture supernatants lysates
  • Recommended Sample Dilution: 25 μL per well of 1:20,000 diluted serum or plasma; cell/tissue culture samples may require dilution in appropriate control medium
  • Assay Run Time: Overnight (16-22 hours) at 2-8°C
  • Research Category: Cardiovascular
  • Research Subcategory: Metabolism

特徴および利点

Design your multiplex kit by choosing available analytes within this panel.

法的情報

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

ピクトグラム

Skull and crossbonesHealth hazardCorrosionEnvironment

シグナルワード

Danger

危険有害性の分類

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

ターゲットの組織

Respiratory Tract

保管分類コード

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

MAP2MAG-76K-01:
MAP2MAG-76K-02:
MAP2MAG-76K-04:
MAP2MAG-76K-06:
MAP2MAG-76K-03:
MAP2MAG-76K-05:
MAP2MAG-76K:


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R B Kostogrys et al.
The journal of nutrition, health & aging, 19(7), 710-718 (2015-07-22)
Low Carbohydrate High Protein diet represents a popular strategy to achieve weight loss. The aim of this study was to characterize effects of low carbohydrate, high protein diet (LCHP) on atherosclerotic plaque development in brachiocephalic artery (BCA) in apoE/LDLR-/- mice
Edward O List et al.
Molecular endocrinology (Baltimore, Md.), 27(3), 524-535 (2013-01-26)
GH receptor (GHR) gene-disrupted mice (GHR-/-) have provided countless discoveries as to the numerous actions of GH. Many of these discoveries highlight the importance of GH in adipose tissue. For example GHR-/- mice are insulin sensitive yet obese with preferential
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Annually, there are over 2 million incidents of traumatic brain injury (TBI) and treatment options are non-existent. While many TBI studies have focused on the brain, peripheral contributions involving the digestive and immune systems are emerging as factors involved in
Nigel Davies et al.
Molecular therapy. Nucleic acids, 24, 369-384 (2021-04-20)
Lipid nanoparticles (LNPs) are the most clinically advanced delivery system for RNA-based drugs but have predominantly been investigated for intravenous and intramuscular administration. Subcutaneous administration opens the possibility of patient self-administration and hence long-term chronic treatment that could enable messenger
Susan J Zunino et al.
The British journal of nutrition, 108(5), 900-909 (2011-11-10)
Obesity is a strong risk factor for the development of CVD, hypertension and type 2 diabetes. The overall goal of the present pilot study was to feed strawberries, in the form of freeze-dried powder, to obese subjects to determine whether

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