MABF216

Anti-Microsialin/CD68 Antibody, clone 9

clone 9, 1 mg/mL, from rat

• 別名: Macrosialin, CD68
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rat
• 品質水準: 100
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: 9, monoclonal
• 交差性: mouse
• 濃度: 1 mg/mL
• テクニック: flow cytometry: suitable
• アイソタイプ: IgG2aκ
• NCBIアクセッション番号: NP_033983
• UniProtアクセッション番号: P31996
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: mouse ... Cd68(12514)

詳細

詳細

Microsialin/CD68, also known as Macrosialin, Gp110, CD_antigen 68, or CD68, and encoded by the gene CD68, is a membrane protein expressed in macrophages (and other cells) that appears to play a role in the phagocytic activities of tissue macrophages both in intracellular lysosomal metabolism but also in extracellular cell to cell interactions and cell pathogen interactions. Microsialin binds to tissue and organ-specific lectins or selectins mediating homing of macrophage subsets to particular sites. Also, rapid recirculation of Microsialin from the endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selection-bearing substrates or other cells. Microsialin is expressed in blood monocytes and tissue macrophages primarily but is also found expressed in lymphocytes, fibroblasts and endothelial cells so it is not an exclusive marker for macrophages. Also Microsialin is expressed on many tumor cells which seem to allow the tumor cells to attach to selectins on the vascular endothelium facilitating their dissemination to secondary sites.

免疫原

Recombinant protein corresponding to mouse Microsialin/CD68.

アプリケーション

Research Category
炎症及び免疫

Research Sub Category
免疫グロブリン及び免疫

Anti-Microsialin/CD68 Antibody, clone 9 is an antibody against Microsialin/CD68 for use in flow cytometry.

物理的形状

Protein G Purified

Format: Purified

Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable