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由来生物
mouse
品質水準
抗体製品の状態
purified immunoglobulin
抗体製品タイプ
primary antibodies
クローン
33.1, monoclonal
化学種の反応性
human
テクニック
ELISA: suitable
immunohistochemistry: suitable
アイソタイプ
IgG1κ
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... KLK13(26085)
詳細
Kallikreins-related peptidases (KLKs) are proteases that are important for the desquamation process of the skin (cell shedding). Kallikreins are also associated with carcinogenesis and some serve as a novel cancer and other disease biomarkers. Kallikrein-13/KLK13 is important in lung cancer by allowing lung adenocarcinoma spreading through promoting the expression of various adhesion molecules and it in assisting in extracellular matrix protein degradation necessary for movement. Kallikrein-13/KLK13 also plays a role in salivary tumors and ovarian cancer as well as other cancers in a similar fashion. In both normal and cancerous tissues, Kallikrein-13/KLK13 is secreted into the ECM and expressed in many tissues in both the embryo and adult.
免疫原
Recombinant protein corresponding to Human Kallikrein-13/KLK13.
アプリケーション
Immunohistochemistry Analysis: A representative lot of this antibody detected Kallikrein-13/KLK13 in Normal ovarian surface epithelium and epithelial ovarian cancer tissues (White et al., (2009) British Journal of Cancer. 101:1107-1113).
ELISA: A representative lot of this antibody detected various Kallikrein-13/KLK13 concentrations of several human tissues (Kapadia et al., (2003) Clinical chemistry. 49(1):77–86).
ELISA: A representative lot of this antibody detected various Kallikrein-13/KLK13 concentrations of several human tissues (Kapadia et al., (2003) Clinical chemistry. 49(1):77–86).
This Anti-Kallikrein-13/KLK13 Antibody, clone 33.1 is validated for use in Immunohistochemistry and ELISA for the detection of Kallikrein-13/KLK13.
品質
Evaluated by Immunohistochemistry in human lung and human prostate tissue.
Immunohistochemistry Analysis: A 1:50 dilution of this antibody detected Kallikrein-13/KLK13 in human prostate tissue.
Immunohistochemistry Analysis: A 1:50 dilution of this antibody detected Kallikrein-13/KLK13 in human prostate tissue.
ターゲットの説明
30 kDa calculated
物理的形状
Format: Purified
Purified mouse monoclonal IgG1k in 0.1 M Sodium Bicarbonate buffer pH8.2 without preservatives.
その他情報
Concentration: Please refer to lot specific datasheet.
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保管分類コード
12 - Non Combustible Liquids
WGK
nwg
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
MABC971:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Human kallikrein 13: production and purification of recombinant protein and monoclonal and polyclonal antibodies, and development of a sensitive and specific immunofluorometric assay.
Kapadia, Carl, et al.
Clinical Chemistry, 49, 77-86 (2003)
N M A White et al.
British journal of cancer, 101(7), 1107-1113 (2009-08-27)
The human kallikrein-related peptidase family consists of 15 genes. Twelve of these genes are overexpressed in ovarian cancer and may represent potential markers for diagnosis, prognosis, and/or response to treatment. The aim of this study was to determine the prognostic
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