由来生物
mouse
品質水準
抗体製品の状態
ascites fluid
抗体製品タイプ
primary antibodies
クローン
R4, monoclonal
交差性
guinea pig, bovine, mouse, rat, human
メーカー／製品名
Chemicon®
テクニック
western blot: suitable
アイソタイプ
IgG2b
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
ターゲットの翻訳後修飾
unmodified
遺伝子情報
bovine ... Gnai1(281790)
human ... GNAI1(2770)
mouse ... Gnai1(14677)
rat ... Gnai1(25686)
特異性
Gialpha-1. Strong reactivity with rat (100%), mouse (78%), bovine (74%) and guinea pig (48%). Slight reactivity with human (31%). Specificity confirmed by Western blot versus bovine Galphat, rat Goalpha, rat Gialpha-1, Gialpha-2, rat Gialpha-3, bovine Gsalpha, and murine GoalphaA and GoalphaB.
免疫原
Rat brain G-proteins purified by the method of Sternweis and Robishaw (Sternweis & Robishaw, 1984).
アプリケーション
Research Category
細胞シグナル伝達
細胞シグナル伝達
Research Sub Category
GPCR、cAMP/cGMP及びカルシウムシグナル伝達
GPCR、cAMP/cGMP及びカルシウムシグナル伝達
Anti-G Protein Giα-1 Antibody, clone R4 detects level of G Protein Giα-1 & has been published & validated for use in WB.
Western blot 1:500 - 1:2000.
Labels a single protein band of 39 - 42 kDa in bovine and rat membranes.
Optimal working dilutions must be determined by end user.
Labels a single protein band of 39 - 42 kDa in bovine and rat membranes.
Optimal working dilutions must be determined by end user.
物理的形状
Liquid ascites, containing sodium azide as a preservative.
保管および安定性
Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
法的情報
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.
Sternweis, P C and Robishaw, J D
The Journal of Biological Chemistry, 259, 13806-13813 (1984)
E Burgos-Ramos et al.
Neuroscience, 154(4), 1458-1466 (2008-06-17)
Minocycline is a semi-synthetic second-generation tetracycline known to improve cognition in amyloid precursor protein transgenic mice. Whether it can protect the somatostatin (SRIF) receptor-effector system, also involved in learning and memory, from alterations induced by chronic i.c.v. infusion of beta-amyloid
Activity of the hippocampal somatostatinergic system following daily administration of melatonin.
Rosa Maria Izquierdo-Claros, Maria Del Carmen Boyano-Adanez, Eduardo Arilla-Ferreiro
Brain Research Molecular Brain Research null
Acutely administered melatonin decreases somatostatin-binding sites and the inhibitory effect of somatostatin on adenylyl cyclase activity in the rat hippocampus.
Rosa Maria Izquierdo-Claros, Maria del Carmen Boyano-Adanez Md, Eduardo Arilla-Ferreiro
Journal of Pineal Research null
Apurva A Javkhedkar et al.
Physiological reports, 3(11) (2015-11-26)
Previously we have shown that in spontaneously hypertensive rats (SHR) renal angiotensin (Ang) II receptor (AT1R) upregulation leads to overstimulation of Na/K-ATPase by Ang II. There are reports that antioxidants can reduce oxidative stress and blood pressure (BP) in SHR
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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