MAB2605

Anti-ATG5 Antibody, clone 177.19

clone 177.19, from mouse

• 別名: APG5 autophagy 5-like, APG5 autophagy 5-like (S. cerevisiae), APG5 (autophagy 5, S. cerevisiae)-like, ATG5 autophagy related 5 homolog (S. cerevisiae), ATG5 autophagy related 5-like, Apoptosis-specific protein
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 100
• 抗体製品の状態: purified antibody
• 抗体製品タイプ: primary antibodies
• クローン: 177.19, monoclonal
• 化学種の反応性: human
• テクニック: immunoprecipitation (IP): suitable; western blot: suitable
• アイソタイプ: IgG2bκ
• NCBIアクセッション番号: NM_004849.2
• UniProtアクセッション番号: Q9H1Y0
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... ATG5(9474)

詳細

詳細

ATG5 is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form autophagosomes. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. Conjugation to ATG12 is essential for autophagy, but is not required for association with isolation membrane. ATG5 also plays an important role in the apoptotic process. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity

特異性

Other species have not been tested.

The antibody reacts with the 50 kDa ATG5 protein.

免疫原

Linear Peptide, aa: 8-318

アプリケーション

Research Category
アポトーシス及び癌

Research Sub Category
アポトーシス-追加

Immunoprecipitation: HeLa cell lysate

This Anti-ATG5 Antibody, clone 177.19 is validated for use in WB, IP for the detection of ATG5.

品質

Western Blot Analysis: 0.5 ug/mL of this antibody detected ATG5 on HeLa cell lysate.

ターゲットの説明

50 kDa

関連事項

Replaces: MABC137

物理的形状

Protein G Purified

Format: Purified

Purified in 0.1M Tris-Glycine (pH7.4) 150mM NaCl with 0.05% NaN3.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

アナリシスノート

Control
Western Blot and Immunoprecipitation: HeLa cell lysate.

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable