由来生物
rabbit
品質水準
抗体製品の状態
purified antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
形状
liquid
含みます
≤0.1% sodium azide as preservative
化学種の反応性
human
メーカー／製品名
Calbiochem®
保管条件
do not freeze
アイソタイプ
IgG
輸送温度
wet ice
保管温度
2-8°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... CTSD(1509)
詳細
Anti-Cathepsin D (Ab-2), rabbit polyclonal, recognizes the ~52 kDa latent form and ~34 kDa subunit in breast carcinoma tissue. It is validated for WB and IHC with frozen and paraffin sections.
Purified rabbit polyclonal antibody. Recognizes the ~52 kDa latent form and the ~34 kDa (but not the ~14 kDa) active subunit of cathepsin D.
Recognizes the ~52 kDa latent form D and the ~34 kDa subunit, but not the ~14 kDa subunit of cathepsin D in breast carcinoma tissue extracts.
免疫原
Human
purified human liver cathepsin D
アプリケーション
Frozen Sections (5 µg/ml)
Immunoblotting (2.5 µg/ml)
Paraffin Sections (5 µg/ml, trypsin pre-treatment required)
Immunoblotting (2.5 µg/ml)
Paraffin Sections (5 µg/ml, trypsin pre-treatment required)
包装
Please refer to vial label for lot-specific concentration.
警告
Toxicity: Standard Handling (A)
物理的形状
In 50 mM sodium phosphate buffer, 0.2% gelatin, pH 7.5.
アナリシスノート
Positive Control
HT1080 concentrated conditioned medium or breast carcinoma tissue
HT1080 concentrated conditioned medium or breast carcinoma tissue
その他情報
For optimal results in immunoblotting, conditioned media from HT1080 cells should be concentrated 10-20X prior to loading. Antibody should be titrated for optimal results in individual systems.
Rochefort, H. 1992. Eur. J. Cancer28A, 1780.
Rochefort, H. 1990. In Seminars in Cancer Biology, ed. M. M. Gottesman. Vol. 1(2), 153.
Westly, B. and Rochefort, H. 1980. Cell20, 352.
Barret, A. J. 1977. In Proteinases in Mammalian Cells and Tissues, ed. Barret, A. J., North Holland, New York, p 209.
Rochefort, H. 1990. In Seminars in Cancer Biology, ed. M. M. Gottesman. Vol. 1(2), 153.
Westly, B. and Rochefort, H. 1980. Cell20, 352.
Barret, A. J. 1977. In Proteinases in Mammalian Cells and Tissues, ed. Barret, A. J., North Holland, New York, p 209.
法的情報
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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保管分類コード
10-13 - German Storage Class 10 to 13
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
S N Wickramasinghe et al.
British journal of haematology, 101(2), 245-250 (1998-06-03)
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Journal of Huntington's disease, 5(3), 249-260 (2016-10-01)
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