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Merck

HND3MAG-39K

Millipore

MILLIPLEX® Human Neurological Disorders Magnetic Bead Panel 3 - Neuroscience Multiplex Assay

The analytes available for this multiplex kit are: AGT, Contactin-1, Fetuin A, Kallikrein-6, OPN, sSOD1, sSOD2

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About This Item

UNSPSCコード:
12161503
eCl@ss:
32161000
NACRES:
NA.84

品質水準

化学種の反応性

human

メーカー/製品名

Milliplex®

assay range

accuracy: 69-92%
(Cerebrospinal fluid (CSF))

accuracy: 71-107%
(Serum)

standard curve range: 0.03-25 ng/mL
(SOD2)

standard curve range: 0.04-30 ng/mL
(Kallikrein-6)

standard curve range: 0.04-30 ng/mL
(SOD1)

standard curve range: 0.08-60 ng/mL
(Contactin-1)

standard curve range: 0.14-100 ng/mL
(Osteopontin (OPN))

standard curve range: 1.37-1,000 ng/mL
(AGT)

standard curve range: 4.12-3,000 ng/mL
(Fetuin A)

テクニック

multiplexing: suitable

検出方法

fluorometric (Luminex xMAP)

輸送温度

wet ice

詳細

Neurological disorders are diseases of the brain, spinal cord, and nerves. There are more than 600 diseases of the nervous system, such as Multiple sclerosis (MS), Alzheimer′s disease (AD), amyotrophic lateral sclerosis (ALS), Parkinson′s disease (PD), and stroke as well as frontotemporal dementia and many others. Identification of biomarkers for these neurological disorders allows scientists to identify early signs of neurological damage, track disease progression, and monitor efficacy of therapeutic treatment. The MILLIPLEX® 7-plex Human Neurological Disorders Bead Panel 3 is designed for the simultaneous measurement of multiple biomarkers in human cerebrospinal fluid (CSF), plasma, and serum using the Luminex® xMAP® instrument platform. The kit contains enough material to analyze 38 samples in duplicate, including the standard curve and two quality controls.

NOTE: For serum and plasma samples Fetuin A requires a higher (1:4000) dilution and therefore must be assayed alone as a singleplex. For serum or plasma samples all analytes, except Fetuin A, require a 1:50 dilution and may be assayed together as a multiplex.

The MILLIPLEX® Human Neurological Disorders Bead Panel 3 (Cat. No. HND3MAG-39K) is to be used for the simultaneous quantification of the following 7 analytes in any combination in CSF, serum or plasma samples: Angiotensinogen (AGT), Contactin-1, Fetuin A, Kallikrein-6, Osteopontin (OPN), Soluble Superoxide Dismutase 1 (SOD1), Soluble Superoxide Dismutase 2 (SOD2).

NOTE: For serum and plasma samples Fetuin A requires a higher (1:4000) dilution and therefore must be assayed alone as a singleplex. For serum or plasma samples all analytes, except Fetuin A, require a 1:50 dilution and may be assayed together as a multiplex.

Panel Type: Neuroscience

特異性

Cross Reactivty
There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel.

アプリケーション

  • Analytes: Angiotensinogen (AGT), Contactin-1, Fetuin A, Kallikrein-6, Osteopontin (OPN), Soluble Superoxide Dismutase 1 (SOD1), Soluble Superoxide Dismutase 2 (SOD2)
  • Recommended Sample type: CSF, serum, and plasma
  • Recommended Sample dilution: 1:100 for CSF, 1:50 for serum and plasma for all analytes except Fetuin A, 1:4000 for serum and plasma for Fetuin A
  • NOTE: Fetuin A cannot be assayed along with other analytes in serum/plasma samples. Fetuin A should be diluted 1:4000 in the kit Assay Buffer and analyzed as a singleplex for serum and plasma samples
  • Assay Run Time: One day or Overnight
  • Research Category: Neuroscience

特徴および利点

Design your multiplex kit by choosing available analytes within this panel.

包装

Everything you need in a single kit.

保管および安定性

Recommended storage for kit components is 2 - 8°C.

その他情報

Sensitivity: Refer to kit protocol for sensitivities of individual biomarkers.

法的情報

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

ピクトグラム

Health hazardCorrosionExclamation markEnvironment

シグナルワード

Danger

危険有害性の分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

ターゲットの組織

Respiratory Tract

保管分類コード

10 - Combustible liquids


適用法令

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Jan Code

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関連コンテンツ

Learn how multiplex detection of Alzheimer’s disease biomarkers, using the MILLIPLEX®Human Amyloid Beta and Tau Magnetic Bead Panel, allows for a different perspective on neurodegenerative disease research.

Neuroscience multiplex assays, such as MILLIPLEX® multiplex assays, enable simultaneous measurement of neuroscience-related biomarkers to gain a better picture of neurodegenerative diseases, neurological disorders, and neuropeptide/neurohormone signaling.

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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