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Merck

HCVD6MAG-67K

Millipore

MILLIPLEX® Human Cardiovascular Disease Magnetic Bead Panel 6 - Cardiovascular Disease (CVD) Multiplex Assay

The analytes available for this multiplex kit are: sCD14, DPP4/sCD26, Endostatin, pGRN, LRG1, MCAM, ucMGP

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About This Item

UNSPSCコード:
12161503
eCl@ss:
32161000
NACRES:
NA.47

品質水準

化学種の反応性

human

メーカー/製品名

Milliplex®

assay range

accuracy: 92%
(Endostatin)

accuracy: 95%
(ucMGP)

accuracy: 97%
(DPP4/sCD26)

sensitivity: 0.007 ng/mL
(MinDC+2SD; Endostatin)

sensitivity: 0.014 ng/mL
(MinDC+2SD; pGRN)

sensitivity: 0.015 ng/mL
(MinDC+2SD; LRG1)

sensitivity: 0.016 ng/mL
(MinDC+2SD; MCAM)

sensitivity: 0.016 ng/mL
(MinDC+2SD; sCD14)

sensitivity: 0.041 ng/mL
(MinDC+2SD; DPP4)

sensitivity: 0.052 ng/mL
(MinDC+2SD; ucMGP)

standard curve range: 0.002-10 ng/mL
(Endostatin)

standard curve range: 0.01-40 ng/mL
(sCD14)

standard curve range: 0.024-100 ng/mL
(LRG1)

standard curve range: 0.024-100 ng/mL
(MCAM)

standard curve range: 0.024-100 ng/mL
(pGRN)

standard curve range: 0.049-200 ng/mL
(DPP4/sCD26)

standard curve range: 0.049-200 ng/mL
(ucMGP)

inter-assay cv: <10%
intra-assay cv: <5%
(DPP4/sCD26)

inter-assay cv: <10%
intra-assay cv: <5%
(Endostatin)

inter-assay cv: <10%
intra-assay cv: <5%
(LRG1)

inter-assay cv: <10%
intra-assay cv: <5%
(MCAM)

inter-assay cv: <10%
intra-assay cv: <5%
(pGRN)

inter-assay cv: <20%
intra-assay cv: <10%
(ucMGP)

inter-assay cv: <20%
intra-assay cv: <5%
(sCD14)

テクニック

multiplexing: suitable

検出方法

fluorometric (Luminex xMAP)

輸送温度

ambient

詳細

Cardiovascular disease is one of the major causes of death worldwide. Assessing the risk for cardiovascular disease is an important aspect in clinical decision making and setting a therapeutic strategy. The use of serological biomarkers may significantly facilitate risk factor identification. By exploring new applications of established biomarkers and new approaches to identify novel biomarkers, researchers continue to refine the mechanistic understanding of the biology of CVD diseases.

The MILLIPLEX® Human Cardiovascular Disease (CVD) Panel 6 is a 7-plex kit may be used to simultaneously quantify any or all the following analytes in human serum, plasma, and tissue culture samples: Soluble Cluster of Differentiation 14 (sCD14), Dipeptidyl Peptidase-4 (DPP4/DPPIV) / Soluble Cluster of Differentiation 26 (sCD26), Endostatin / Collagen Alpha-1 (XVIII) (COL181A), Progranulin (pGRN) / Proepithelin (PEPI) / PC Cell-derived Growth Factor (PCDGF) / Acrogranin / Paragranulin, Leucine-rich Alpha-2-Glycoprotein 1 (LRG1), Melanoma Cell Adhesion Molecule (MCAM) / Soluble Cluster of Differentiation 146 (sCD146) / Cell Surface Glycoprotein MUC18, Uncarboxylated Matrix Gamma-Carboxyglutamate (Gla) Protein (ucMGP). This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Cardiovascular

特異性

Cross Reactivty
There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel.
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

アプリケーション

  • Analytes: Monocyte Differentiation Antigen (CD14/sCD14), Dipeptidyl Peptidase-4 (DPP4/sCD26), Endostatin, Leucine-rich α-2-glycoprotein 1 (LRG1), Cell Surface Glycoprotein (MCAM/ MUC18/sCD146), Progranulin (pGRN), Uncarboxylated Matrix Gla Protein (ucMGP)
  • Recommended Sample Type:
  • Human serum, plasma, cell/tissue culture supernatants and lysates
  • Recommended Sample Dilution: 25 μL per well of 1:500 diluted serum or plasma; cell/tissue culture supernatants or lysates may be used undiluted ore or diluted in appropriate control medium
  • Assay Run Time: Overnight (16-18 hours)at 2-8°C will yield optimal sensitivity.2- A 2 hour incubation at room temperature (20-25°C) may also be used.
  • Research Category: Cardiovascular Disease
  • Research Subcategory: Metabolic Disorders

特徴および利点

Design your multiplex kit by choosing available analytes within this panel.

包装

Everything you need in a single kit.

保管および安定性

Recommended storage for kit components is 2 - 8°C.

その他情報

Please contact Technical Service for linearity of dilution.

法的情報

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

ピクトグラム

Health hazardCorrosionExclamation markEnvironment

シグナルワード

Danger

危険有害性の分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

ターゲットの組織

Respiratory Tract

保管分類コード

10 - Combustible liquids


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

HCVD6MAG-67K-05:
HCVD6MAG-67K-07:
HCVD6MAG-67K-03:
HCVD6MAG-67K:
HCVD6MAG-67K-04:
HCVD6MAG-67K-01:
HCVD6MAG-67K-06:
HCVD6MAG-67K-02:


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関連コンテンツ

Learn about biomarkers of cardiovascular disease (CVD) and discover how multiplex CVD panels, such as MILLIPLEX® multiplex assays, are being used to increase the efficiency of biomarker discovery for CVD research.

心血管疾患(CVD)バイオマーカーの詳細を確認し、MILLIPLEX® マルチプレックスアッセイのようなマルチプレックスCVDパネルを用いて、CVD研究のバイオマーカー探索の効率を高める方法をご覧ください。

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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