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Merck

HCCBP3MAG-58K

Millipore

MILLIPLEX® Human Circulating Cancer Biomarker Magnetic Bead Panel 3 - Cancer Multiplex Assay

Circulating Cancer Biomarker Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple oncology biomarkers in various tumor types in human serum, plasma and cell culture samples.

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About This Item

UNSPSCコード:
12161503
eCl@ss:
32161000
NACRES:
NA.84

品質水準

化学種の反応性

human

メーカー/製品名

Milliplex®

assay range

accuracy: 74-126%
standard curve range: 0.004-3 ng/mL
(Galectin-3)

standard curve range: 0.02-20 ng/mL
(Myeloperoxidase)

standard curve range: 0.03-25 nM
(Sex Hormone Binding Globulin)

standard curve range: 0.03-25 ng/mL
(Ferritin)

standard curve range: 0.07-50 ng/mL
(Catalase, Fibroblast Activation Protein α)

standard curve range: 0.1-75 ng/mL
(Melanoma Inhibitory Activity Protein)

standard curve range: 0.27-200 ng/mL
(Cathepsin D, IGFBP3)

テクニック

multiplexing: suitable

検出方法

fluorometric (Luminex xMAP)

輸送温度

wet ice

詳細

Circulating cancer biomarkers give insight beyond intracellular oncogenesis and into how the body responds to the presence of a tumor, the dysregulation of homeostasis, and the relationship between a tumor and its environment. Multianalyte panels have become essential tools that enable researchers to measure cancer biomarkers simultaneously, teasing out these relationships and applying them to understand tumor biology.

MILLIPLEX® Human Circulating Biomarker Panel 3 is an 8-plex kit to be used for the simultaneous quantification or any or all of the following analytes in serum, plasma and tissue/cell lysate and culture supernatant samples: Galectin-3, Cathepsin D, Fibroblast activation protein alpha (FAP), Melanoma inhibitory activity protein (MIA), Myeloperoxidase, Sex hormone binding globulin (SHBG), Insulin like growth factor binding protein 3 (IGFBP3), and Ferritin. This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Circulating Cancer

特異性

Cross Reactivty
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

アプリケーション

  • Analytes: Cathepsin D, Ferritin, Fibroblast Activation Protein (FAP), Galectin-3, IGFBP3, Melanoma Inhibitory Activty Protein (MIA), Myeloperoxidase (MPO), Sex Hormone Binding Globulin (SHGB)
  • Recommended Sample Type: Human serum, plasma or tissue/cell culture supernatants or lysates e
  • Recommended Sample Dilution: 25 μL of 1:50 diluted plasma or serum, or 25 μL of diluted tissue/cell lysate or culture supernatant per well (dilution factors may vary). Note: If IGFBP3 is included in the assay, then the recommended dilution for the assay is 1:200
  • Assay Run Time: Overnight (16-18 hr) at 2-4°C
  • Research Category: Cancer

特徴および利点

Design your multiplex kit by choosing available analytes within this panel.

包装

Everything you need in a single kit.

保管および安定性

Recommended storage for kit components is 2 - 8°C.

アナリシスノート

SHBG Standard was calibrated against WHO standard 08/266 and 250 ng/mL standard was equivalent to 25 nM of WHO standard

その他情報

Sensitivity: Refer to kit protocol for sensitivities of individual biomarkers.

法的情報

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

ピクトグラム

Skull and crossbonesEnvironment

シグナルワード

Danger

危険有害性情報

危険有害性の分類

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

保管分類コード

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

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Jan Code

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試験成績書(COA)

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以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Juan Pablo Hinestrosa et al.
Communications medicine, 2, 29-29 (2022-05-24)
Detecting cancer at early stages significantly increases patient survival rates. Because lethal solid tumors often produce few symptoms before progressing to advanced, metastatic disease, diagnosis frequently occurs when surgical resection is no longer curative. One promising approach to detect early-stage

関連コンテンツ

Detection of cancer biomarkers through multiplex cancer assays can accelerate studies of normal homeostasis and tumorigenic processes. See how MILLIPLEX® multiplex cancer assays are advancing various cancer research areas including lung cancer, breast cancer, and immuno-oncology research.

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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