FCMAB214P

Milli-Mark^® Anti-CD117 Antibody, c-kit-PE, clone 104D2

clone 104D2, Milli-Mark^®, from mouse

• 別名: Mast/stem cell growth factor receptor, SCFR, Tyrosine-protein kinase Kit, Proto-oncogene c-Kit
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 100
• 結合体: PE
• 抗体製品の状態: purified antibody
• 抗体製品タイプ: primary antibodies
• クローン: 104D2, monoclonal
• 化学種の反応性: human
• メーカー／製品名: Milli-Mark^®
• テクニック: flow cytometry: suitable
• アイソタイプ: IgG1κ
• NCBIアクセッション番号: NP_000213
• UniProtアクセッション番号: P10721
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... KIT(3815) ; mouse ... Kit(16590)

詳細

詳細

CD117 is a 145 kDa transmembrane protein which belongs to the class III receptor tyrosine kinase family. The extracellular region consists of five immunoglobulin-like domains where the second and third loops are thought to be involved in ligand binding (Ashman, 1997; Bühring, 1995). CD117 has been shown to be a marker for tissue mast cells, hematopoietic stem cells, and progenitor cells in normal human bone marrow. The majority of CD117-positive marrow cells (50-70%) co-express CD34 and comprise progenitor cells and their precursors of all hematopoietic lineages. Apart from mast cells, CD117 is essentially absent from mature hematopoietic cells. Although CD117 is primarily a marker for non-lymphoid progenitor cells in the hematopoietic cells/tissues, including melanocytes, embryonic brain, and the reproductive system (Ashman, 1997). Anti-CD117, 104D2, was included in the Sixth International Workshop and Conference on Human Leucocyte differentiation Antigens, and studies by different laboratories confirmed its reactivity with CD117 (Ashman, 1997).

特異性

Antibody recognizes Human CD117 antigen.

免疫原

MOLM-1 megakaryocytic cell line.

アプリケーション

Research Category
炎症及び免疫

Research Sub Category
免疫グロブリン及び免疫

Milli-Mark Anti-CD117 Antibody, c-kit-PE, clone 104D2 detects level of CD117 & has been published & validated for use in FC.

品質

Evaluated by flow cytometry using TF-1 cells

ターゲットの説明

145 kDa (Ashman, 1997; Buhring, 1995)

物理的形状

Protein A purified

Purified Mouse monoclonal IgG1 conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

保管および安定性

Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.

アナリシスノート

Control
TF-1 cells

法的情報

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable