由来生物
rabbit
品質水準
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
精製方法
affinity chromatography
化学種の反応性
human
テクニック
immunocytochemistry: suitable
immunofluorescence: suitable
western blot: suitable
UniProtアクセッション番号
輸送温度
wet ice
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... KIF5A(3798)
詳細
Kinesin heavy chain isoform 5A, also known as Kinesin heavy chain neuron-specific 1 or Neuronal kinesin heavy chain (NKHC), and encoded by the gene name KIF5A or NKHC1, are members of the kinesin superfamily of proteins (KIFs). These proteins are microtubuledependent motors that slide along microtubules and transport cellular organelles and mRNA to different parts of the cell. In neurons, KIF5 performs this role in an anterograde fashion from the neuronal cell body to axonal or dendritic terminals. KIF5 was initially differentiated from the ubiquitously expressed kinesin as being highly enriched in subsets of neurons and selectively concentrated in the cell body. KIF5 has at least three known isoforms; KIF5A (117 kDa), KIF5B (39 kDa), and KIF5C (39 kDa). Mutations in one of the isoforms of KIF5 (KIF5A) is thought to be involved in hereditary spastic paraplegias
特異性
This antibody recognizes all isoforms of KIF5.
免疫原
Epitope: C-terminus
KLH-conjugated synthetic peptide corresponding to the C-terminus of human KIF5.
アプリケーション
Research Sub Category
細胞骨格
細胞骨格
Anti-KIF5 Antibody is an antibody against KIF5 for use in western blotting, ICC & immunofluorescence.
Immunocytochemistry Analysis: 5 μg/mL from a representative lot detected KIF5 in K562 cells.
Immunofluorescence Analysis: 20 μg/mL from a representative lot detected KIF5 in K562 cells.
Immunofluorescence Analysis: 20 μg/mL from a representative lot detected KIF5 in K562 cells.
Research Category
Cell Structure
Cell Structure
品質
Evaluated by Western Blotting in K562 cell lysate.
Western Blotting Analysis: 1 μg/mL of this antibody detected KIF5 in K562 cell lysate.
Western Blotting Analysis: 1 μg/mL of this antibody detected KIF5 in K562 cell lysate.
ターゲットの説明
~116 kDa observed. Uncharacterized bands may be observed in some lysate(s).
物理的形状
Affinity
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
保管および安定性
Stable for 1 year at 2-8°C from date of receipt.
その他情報
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
12 - Non Combustible Liquids
WGK
WGK 2
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
ABT405:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
M Cecilia Caino et al.
Nature communications, 7, 13730-13730 (2016-12-20)
The role of mitochondria in cancer is controversial. Using a genome-wide shRNA screen, we now show that tumours reprogram a network of mitochondrial dynamics operative in neurons, including syntaphilin (SNPH), kinesin KIF5B and GTPase Miro1/2 to localize mitochondria to the
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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