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由来生物
rabbit
品質水準
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
精製方法
affinity chromatography
化学種の反応性
human
化学種の反応性（ホモロジーによる予測）
chimpanzee (based on 100% sequence homology), primate (based on 100% sequence homology), monkey (based on 100% sequence homology), baboon (based on 100% sequence homology)
テクニック
immunohistochemistry: suitable
western blot: suitable
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... LGALS7B(653499)
詳細
Galectins are a family of carbohydrate binding proteins. Galectin-7 was initially isolated from human keratinocytes as a novel member of S-lectin family that was responsive to retinoic acid but not detectable in epidermal tumors or squamous carcinomas. It is an early transcriptional target of the tumor suppressor P53 and inducible by UV radiation as well. Galectin-7 is also an enhancer of apoptosis, whereas galectin-1 induces tumorigenicity and resistance to apoptosis in several types of cancers. Recent research demonstrates that Galectin-7 acts as an adhesion molecule during implantation, and increased expression of Galectin-7 is associated with miscarriage, thus Galectin-7 is also being studied as a possible biomarker for miscarriage prediction.
免疫原
KLH-conjugated beta-galactose binding region corresponding to human Galectin-7.
アプリケーション
Research Category
細胞骨格
細胞骨格
Research Sub Category
接着分子（CAM）
接着分子（CAM）
Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected Galectin-7 in human skin and human larynx tissue.
This Anti-Galectin-7 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of Galectin-7.
品質
Evaluated by Western Blotting in human skin tissue lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Galectin-7 in 10 µg of human skin tissue lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Galectin-7 in 10 µg of human skin tissue lysate.
ターゲットの説明
~16 kDa observed
物理的形状
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
保管および安定性
Stable for 1 year at 2-8°C from date of receipt.
その他情報
Concentration: Please refer to lot specific datasheet.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
F Bernerd et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(20), 11329-11334 (1999-09-29)
Galectin-7 is a beta-galactoside binding protein specifically expressed in stratified epithelia and notably in epidermis, but barely detectable in epidermal tumors and absent from squamous carcinoma cell lines. Galectin-7 gene is an early transcriptional target of the tumor suppressor protein
Galectin-7 acts as an adhesion molecule during implantation and increased expression is associated with miscarriage.
Menkhorst, EM; Gamage, T; Cuman, C; Kaitu'u-Lino, TJ; Tong, S; Dimitriadis, E
Placenta null
Batya Barkan et al.
Oncotarget, 4(2), 256-268 (2013-03-27)
Galectins are a family of β-galactoside-binding lectins that exert diverse extracellular and intracellular effects. Galectin-7 and galectin-1 show opposing effects on proliferation and survival in different cell types. Galectin-7 is a p53-induced gene and an enhancer of apoptosis, whereas galectin-1
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