ABS811

Anti-FABP7 Antibody

from rabbit, purified by affinity chromatography

• 別名: Fatty acid-binding protein, brain, Brain lipid-binding protein, BLBP, Brain-type fatty acid-binding protein, B-FABP, Fatty acid-binding protein 7, Mammary-derived growth inhibitor related, FABP7
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 化学種の反応性: human
• テクニック: immunohistochemistry: suitable; western blot: suitable
• UniProtアクセッション番号: O15540
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... FABP7(2173)

詳細

詳細

FABP7 is a member of the large family of hydrophobic ligand-binding proteins (FABPs). FABP proteins are involved in lipid metabolism, including uptake and intracellular trafficking of fatty acids and retinoids. In addition, they play a role in gene regulation, cell signaling, cell growth and differentiation. Several reports have suggested a possible role for the different FABP proteins in cancer biology, linking their levels with either increasing or decreasing the degree of malignancy. Nine FABPs (FABP1-FABP9) have been identified. FABP7 is a brain-specific protein that is required for the establishment of the radial glial fiber system in the developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers. It is expressed at high levels in the developing central nervous system. FABP7 has also been found in melanocytic lesions and has shown to regulate proliferation and invasion in melanoma cells in vitro, suggesting that it may play a role in cell proliferation and invasion.

免疫原

Epitope: Near Center

FABP7 antibody was raised against a 17 amino acid synthetic peptide from near the center of human FABP7.

アプリケーション

Research Category
細胞シグナル伝達

Research Sub Category
発生シグナル伝達

Immunohistochemistry Analysis (IHC): 5 μg/mL from a representative lot detected FABP7 in human breast tissue.

This Anti-FABP7 Antibody is validated for use in Western Blotting_x000D_ and Immunohistochemistry for the detection of FABP7.

品質

Evaluated by Western Blotting in human breast tissue lysate.

Western Blotting Analysis (WB): 1 μg/mL of this antibody detected FABP7 in human breast tissue lysate.

ターゲットの説明

~24 kDa observed. Uncharacterized bands may be observed in some lysate(s).

関連事項

Replaces: MABS184

物理的形状

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

その他情報

Concentration: Please refer to lot specific datasheet.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable