ABN467

Anti-CX3CL1 Antibody

from rabbit, purified by affinity chromatography

• 別名: Fractalkine, C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, Neurotactin, Small-inducible cytokine D1, FKN, NTT, SCYD1, A-152E5.2
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 化学種の反応性: mouse
• 化学種の反応性（ホモロジーによる予測）: human (immunogen homology)
• テクニック: western blot: suitable
• UniProtアクセッション番号: P78423
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: mouse ... Cx3Cl1(20312)

詳細

詳細

C-X3-C motif chemokine 1 (CX3CL1), also known as CX3C membrane-anchored chemokine, Neurotactin (NTT), Small-inducible cytokine D1 (SCYD1), and Fractalkine (FKN), is a CX3C chemokine known to induce adhesion and migration of leukocytes. Recent studies have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-alpha in activated microglia and neuronal cells, and it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Other evidence suggests that CX3CL1 may play a role in regulating leukocyte adhesion and migration processes at the endothelium. Additionally, CX3CL1 is implied to inhibit CX3CR1, which is a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection. CX3CL1 is expressed in small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas.

免疫原

KLH-conjugated linear peptide corresponding to human CX3CL1.

アプリケーション

Research Category
ニューロサイエンス

Research Sub Category
ニューロン発生

Anti-CX3CL1 Antibody is a highly specific rabbit polyclonal antibody, that targets CX3CL1 & has been tested in western blotting.

品質

Evaluated by Western Blotting in C2C12 cell lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected CX3CL1 in 15 µg of C2C12 cell lysate.

ターゲットの説明

~50 kDa observed.

物理的形状

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

アナリシスノート

Control
C2C12 cell lysate

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable