ABE114

Anti-PRDM5 Antibody

from rabbit, purified by affinity chromatography

• 別名: PR domain zinc finger protein 5, PR domain-containing protein 5
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 化学種の反応性: human
• 化学種の反応性（ホモロジーによる予測）: chimpanzee (based on 100% sequence homology)
• テクニック: western blot: suitable
• NCBIアクセッション番号: NP_061169
• UniProtアクセッション番号: Q9NQX1
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... PRDM5(11107)

詳細

詳細

PRDM5 is a member of the PR-domain containing family of tumor suppressors. PRDM5 activates histone methyltransferase G9a and class I histone deacetylases to regulate transcription. PRDM5 typically functions as a transcriptional repressor but can also be an activator for endogenous target genes. PRDM5 has often been found to be silenced in human breast, ovarian and liver cancers and and is a candidate biomarker for certain cancers, such as gastrointestinal cancer. Additional studies have also linked the loss of PRDM5 function to the development and pathogenesis of cervical cancer.

免疫原

Linear peptide corresponding to human PRDM5.

アプリケーション

Use Anti-PRDM5 Antibody (Rabbit Polyclonal Antibody) validated in WB to detect PRDM5 also known as PR domain-containing protein 5.

Western Blot Analysis:1 µg/mL from a representative lot detected PRDM5 on 10 µg of HeLa cell lysate and HeLa nuclear extract.

品質

Evaluated by Western Blot in PC3 cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected PRDM5 on 10 µg of PC3 cell lysate.

ターゲットの説明

~75 kDa observed. Three isoforms at 73, 70, and 13 kDa have been described. Uncharacterized bands between 13 and 73 kDa may be observed in some lysates.

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable