ABE1024

Anti-Oligodendrocyte transcription factor 2 (OLIG2 Antibody)

serum, from guinea pig

• 別名: Oligodendrocyte transcription factor 2, Oligo2
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: guinea pig
• 品質水準: 100
• 抗体製品の状態: serum
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 化学種の反応性: mouse, human
• テクニック: immunohistochemistry: suitable (paraffin); western blot: suitable
• NCBIアクセッション番号: NP_058663
• UniProtアクセッション番号: Q9EQW6
• 輸送温度: dry ice
• ターゲットの翻訳後修飾: unmodified

詳細

詳細

Oligodendrocyte transcription factor 2 (OLIG2), also known as Oligodendrocyte transcription factor 2 Oligo2, Class B basic helix-loop-helix protein 1 (bHLHb1), Class E basic helix-loop-helix protein 19 (bHLHe19), Protein kinase C-binding protein 2, Protein kinase C-binding protein RACK17, is encoded by the gene name OLIG2/ BHLHB1/ BHLHE19/ PRKCBP2/ RACK17. Olig2 is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. It cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Olig2 is an antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development. The restricted expression of Olig2 in oligodendrocytes makes AB9610 an excellent marker of oligodendroglia and oligodendrogliomas in development and mature systems. Olig2 is expressed in the brain and oligodendrocytes. Olig2 is strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.

免疫原

Epitope: Unknown

KLH-conjugated linear peptide corresponding to mouse Oligodendrocyte transcription factor 2 (OLIG2).

アプリケーション

Research Category
ニューロサイエンス

Research Sub Category
発生シグナル伝達

Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Oligodendrocyte transcription factor 2 (OLIG2) in human cortical brain section tissue.

This Anti-Oligodendrocyte transcription factor 2 (OLIG2 antibody is validated for use in WB, IH(P) for the detection of Oligodendrocyte transcription factor 2 (OLIG2.

品質

Evaluated by Western Blotting in mouse brain tissue lysate.

Western Blotting Analysis: A 1:1;000 dilution of this antibody detected Oligodendrocyte transcription factor 2 (OLIG2) in 10 µg of mouse brain tissue lysate.

ターゲットの説明

~37 kDa observed

物理的形状

Unpurified

Guinea pig polyclonal serum with 0.05% sodium azide.

保管および安定性

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

その他情報

Concentration: Please refer to lot specific datasheet.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1