ABD85

Anti-PAX3/7BP Antibody

serum, from rabbit

• 別名: PAX3 binding protein 1, PAX7 binding protein 1, GC-rich sequence DNA-binding factor 1
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: serum
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 化学種の反応性: rat, mouse, human
• テクニック: immunoprecipitation (IP): suitable; western blot: suitable
• UniProtアクセッション番号: Q9Y5B6
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: mouse ... Paxbp1(67367)

詳細

詳細

In skeletal muscles, Pax7 uniquely marks muscle satellite cells and plays some important yet unknown functions at the perinatal stage. Pax3/7BP is a ubiquitously expressed nuclear protein, enriched in Pax7+ muscle precursor cells (MPCs), and serves as an indispensable adaptor for Pax7 to recruit the histone-3-lysine-4 (H3K4) methyltransferase (HMT) complex by bridging Pax7 and Wdr5. Recently, Wu et al. have established Pax3/7BP as an essential adaptor linking Pax3/7 with the H3K4 HMT to regulate the proliferation of muscle progenitor cells.

免疫原

Recombinant protein corresponding to mouse PAX3/7BP.

アプリケーション

Research Category
幹細胞研究

Research Sub Category
筋生理学

発生シグナル伝達

Anti-PAX3/7BP Antibody is an antibody against PAX3/7BP for use in western blotting & IP.

品質

Evaluated by Western Blot in a jurkat cell lysate.
Western Blot Analysis: A 1:1000 dilution of this antibody detected Pax3/7BP in a 10 µg jurkat cell lysate.

ターゲットの説明

~105 kDa observed. Uncharacterized bands may be observed in some lysate(s).

物理的形状

Unpurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1