ABC841

Anti-Caspase-14 Antibody

from rabbit, purified by affinity chromatography

• 別名: Caspase-14, CASP-14
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 化学種の反応性: human
• テクニック: immunohistochemistry: suitable; western blot: suitable
• UniProtアクセッション番号: P31944
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... CASP14(23581)

詳細

詳細

Caspases are a family of cysteine proteases that can be divided into apoptotic and inflammatory caspase subfamilies. Caspase-14 exists as 2 subunits (p19 and p10) and is highly expressed in embryonic but not adult tissues. It is processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in the keratinocyte terminal differentiation, which is important for the formation of the skin barrier.

特異性

This antibody detects the pro-form of Caspase-14 as well as the large subunit cleaved form.

免疫原

KLH-conjugated linear peptide corresponding to 16 amino acids near the C-terminus of human Caspase-14.

アプリケーション

Anti-Caspase-14 Antibody is a highly specific rabbit polyclonal antibody, that targets Caspase 14 & has been tested in western blotting & IHC.

Immunohistochemistry Analysis: 2.5 μg/mL from a representative lot detected Caspase-14 in human liver tissue.

品質

Evaluated by Western Blotting in Jurkat cell lysate with and without blocking peptide.

Western Blotting Analysis: 1 μg/mL of this antibody detected Caspase-14 in Jurkat cell lysate with and without blocking peptide.

ターゲットの説明

~28 kDa observed. Uncharacterized bands may be observed in some lysate(s).

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable