おすすめの製品
由来生物
rabbit
品質水準
抗体製品の状態
serum
抗体製品タイプ
primary antibodies
クローン
polyclonal
交差性
mouse
メーカー/製品名
Chemicon®
テクニック
western blot: suitable
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
ターゲットの翻訳後修飾
unmodified
遺伝子情報
mouse ... Cyp2B10(13088)
詳細
CYP2b10 (Cytochrome P450, family 2, subfamily b, polypeptide 10) is a member of the cytochrome P450 superfamily of monooxygenase enzymes which catalyze many reactions involved in drug metabolism and the synthesis of cholesterol, steroids and other lipids.
特異性
AB9916 is specific for CYP2b10.
免疫原
Epitope: AA I182 – T205
Recombinant 2b10
アプリケーション
This Anti-CYP2b10 Antibody is validated for use in WB for the detection of CYP2b10.
品質
Routinely evaluated by immunoblot.
ターゲットの説明
58kDa
法的情報
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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保管分類コード
10 - Combustible liquids
WGK
WGK 1
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
AB9916:
試験成績書(COA)
製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Shinhee Park et al.
Acta pharmaceutica Sinica. B, 6(5), 475-491 (2016-10-07)
Intestine is responsible for the biotransformation of many orally-exposed chemicals. The constitutive androstane receptor (CAR/Nr1i3) is known to up-regulate many genes encoding drug-metabolizing enzymes and transporters (drug-processing genes/DPGs) in liver, but less is known regarding its effect in intestine. Sixty-day-old
Kentaro Nobutani et al.
Pharmacology research & perspectives, 5(5) (2017-10-04)
Herbal medicines and natural products used for maintenance of health or treatment of diseases have many biological effects, including altering the pharmacokinetics and metabolism of other medications. Daikenchuto (TU-100), an aqueous extract of ginger, ginseng, and Japanese green pepper fruit
Cindy Yanfei Li et al.
Toxicological sciences : an official journal of the Society of Toxicology, 153(2), 282-302 (2016-07-15)
Safety concerns have emerged regarding the potential long-lasting effects due to developmental exposure to xenobiotics. The pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are critical xenobiotic-sensing nuclear receptors that are highly expressed in liver. The goal of this
Xia Wen et al.
The Journal of pharmacology and experimental therapeutics, 344(1), 244-252 (2012-10-12)
Phase II enzymes, including Ugts, Sults, and Gsts, are critical for the disposition and detoxification of endo- and xenobiotics. In this study, the mRNA and protein expression of major phase II enzymes, as well as key regulatory transcription factors, were
p53-mediated regulation of bile acid disposition attenuates cholic acid-induced cholestasis in mice.
Pan Chen et al.
British journal of pharmacology, 174(23), 4345-4361 (2017-09-15)
The tumour suppressor p53 is traditionally recognized as a surveillance molecule to preserve genome integrity. Recent studies have demonstrated that it contributes to metabolic diseases. Here, we investigated the role of p53 in the regulation of bile acid disposition and
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