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由来生物
rabbit
品質水準
抗体製品の状態
serum
抗体製品タイプ
primary antibodies
クローン
polyclonal
化学種の反応性
monkey, human
メーカー／製品名
Chemicon®
テクニック
immunocytochemistry: suitable
western blot: suitable
入力
sample type neural stem cell(s)
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... TOMM20L(387990)
詳細
Presenilin 1 is a protein found in brain cells. Presenilin 1 has a major influence on the risk of contracting alzheimer′s disease. Its function is unknown. However, it may be involved in protein production and trafficking, especially during early development. More than 40 different mutations have been found in the presenilin 1 gene, and these mutations associate with early-onset familial alzheimer′s disease. Mutations in presenilin 1 tend to elevate levels of amyloid beta in the blood, cerebrospinal fluid, and brains of those affected by mutations
特異性
Mitochondria. Recognizes a 62 kD protein of immunoblots of subcellular fractions enriched in mitochondrial fractions.
The antibody shows a moderate titer by ELISA to the immunogen peptide but does not immunoblot any expected presenilin 1 bands. Immunocytochemistry with the serum revealed a mitochondria-like staining that was still present after exhaustive preabsorption with the peptide. The staining co-localizes with CHEMICON′s anti-mitochondria antibody MAB1273.
The antibody shows a moderate titer by ELISA to the immunogen peptide but does not immunoblot any expected presenilin 1 bands. Immunocytochemistry with the serum revealed a mitochondria-like staining that was still present after exhaustive preabsorption with the peptide. The staining co-localizes with CHEMICON′s anti-mitochondria antibody MAB1273.
免疫原
Presenilin 1 peptide conjugated to KLH.
アプリケーション
Research Category
幹細胞研究
幹細胞研究
Research Sub Category
神経幹細胞
神経幹細胞
Anti-Mitochondria Antibody is an antibody against Mitochondria for use in WB & IC.
Immunoblotting: 1:500-1:1000
Immunocytochemistry: 1:100-1:300 on COS7, HeLa, 293 and SK-N-MC cell lines.
Optimal working dilutions must be determined by the end user.
Immunocytochemistry: 1:100-1:300 on COS7, HeLa, 293 and SK-N-MC cell lines.
Optimal working dilutions must be determined by the end user.
ターゲットの説明
62 kDa
物理的形状
Rabbit serum preabsorbed against immunogen peptide. Liquid. Contains 0.01% sodium azide.
保管および安定性
Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze-thaw cycles.
アナリシスノート
Control
HeLa whole cell extract, human neuroblastoma SH-SY5Y cells
HeLa whole cell extract, human neuroblastoma SH-SY5Y cells
法的情報
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
WGK 1
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
AB3598:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
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ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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