AB1254
Anti-Cytochrome P450 Enzyme CYP3A4 Antibody
serum, Chemicon®
別名:
Anti-Anti-CP33, Anti-Anti-CP34, Anti-Anti-CYP3A, Anti-Anti-CYP3A3, Anti-Anti-CYPIIIA3, Anti-Anti-CYPIIIA4, Anti-Anti-HLP, Anti-Anti-NF-25, Anti-Anti-P450C3, Anti-Anti-P450PCN1, Anti-Anti-VDDR3
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すべての画像(1)
About This Item
UNSPSCコード:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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由来生物
rabbit
品質水準
抗体製品の状態
serum
抗体製品タイプ
primary antibodies
クローン
polyclonal
化学種の反応性
human, pig
化学種の反応性（ホモロジーによる予測）
mammals, rat
メーカー／製品名
Chemicon®
テクニック
immunohistochemistry: suitable
western blot: suitable
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
dry ice
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... CYP3A4(1576)
特異性
The rabbit polyclonal serum detects CYP3A4 in humans and rats; by sequence homology of the immunogen used, cross reactivity to CYP3A7, 3A6v4;3A2v1, 3A8, 3A9 may be expected but is untested at this time.
免疫原
A synthetic peptide containing the C-terminal sequence of TVSGA from human CYP3A4. The peptide was coupled to KLH.
アプリケーション
Research Category
代謝
代謝
Research Sub Category
酵素及び生化学
酵素及び生化学
Anti-Cytochrome P450 Enzyme CYP3A4 Antibody detects level of Cytochrome P450 Enzyme CYP3A4 & has been published & validated for use in IH & WB.
Western blot: 1:1000-1:2000: Using microsomal membrane fractions, detects a band at ~54kDa; other bands may be present as well. Antibody has been successfully used to detect CYP3A4 on LICOR fluorescent westerns as well.
Immunohistochemistry: 10% formalin fixed, paraffin embedded tissues 1:200-1:400, microwave-citric acid antigen recovery is suggested.
Optimal working dilutions must be determined by end user.
Immunohistochemistry: 10% formalin fixed, paraffin embedded tissues 1:200-1:400, microwave-citric acid antigen recovery is suggested.
Optimal working dilutions must be determined by end user.
ターゲットの説明
57 kDa
物理的形状
Unpurified
Rabbit antiSerum. Liquid containing no preservative.
保管および安定性
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
アナリシスノート
Control
Liver tissue
Liver tissue
その他情報
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法的情報
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
AB1254:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Pattern of P450 expression at the human blood-brain barrier: roles of epileptic condition and laminar flow.
Ghosh, C; Gonzalez-Martinez, J; Hossain, M; Cucullo, L; Fazio, V; Janigro, D; Marchi, N
Epilepsia null
The application of 3D micropatterning of agarose substrate for cell culture and in situ comet assays.
Emilie Mercey,Patricia Obeid,Denise Glaise,Maria-Luisa Calvo-Mu?oz et al.
Biomaterials null
K Pernelle et al.
Toxicology and applied pharmacology, 254(3), 256-266 (2011-05-17)
In this study, our goal was to develop an efficient in situ test adapted to screen hepatotoxicity of various chemicals, a process which remains challenging during the early phase of drug development. The test was based on functional human hepatocytes
Cellular localization and functional significance of CYP3A4 in the human epileptic brain.
Ghosh, C; Marchi, N; Desai, NK; Puvenna, V; Hossain, M; Gonzalez-Martinez, J; Alexopoulos et al.
Epilepsia null
Manuel Vlach et al.
Cells, 11(23) (2022-12-12)
The goal of this study was to establish a procedure for gene delivery mediated by cationic liposomes in quiescent differentiated HepaRG™ human hepatoma cells. We first identified several cationic lipids promoting efficient gene transfer with low toxicity in actively dividing
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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