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製品種目
Novabiochem®
形状
beads
反応適合性
reaction type: Fmoc solid-phase peptide synthesis
メーカー／製品名
Novabiochem®
アプリケーション
peptide synthesis
官能基
amine
保管温度
2-30°C
詳細
This support comprises the modified Rink amide linker attached via norleucine to aminomethylpolystyrene, and is an ideal tool for the Fmoc SPPS of peptide amides. Cleavage from this resin can be effected by a single step treatment with 95% TFA, providing peptide amides in high yields and purities.
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
アプリケーション
- Second generation amphiphilic poly-lysine dendrons inhibit glioblastoma cell proliferation without toxicity for neurons or astrocytes: Uses Rink Amide AM resin with a 0.71mmol/g loading capacity for synthesizing amphiphilic dendritic amides. (Janiszewska et al., 2016).
- The Role of Phosphoglycans in the Susceptibility of Leishmania mexicana to the Temporin Family of Anti-Microbial Peptides: Describes peptide synthesis on Rink Amide AM resin with a 0.79 mmol/g loading capacity. (Eggimann et al., 2015).
関連事項
Replaces: 01-64-0038
アナリシスノート
Colour (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.40 - 0.80 mmol/g
TNBS-Test: passes test
Swelling Volume (in DMF): lot specific result
Swelling Volume (in CH₂Cl₂): lot specific result
Total swelling volume acc. Houben Weyl (in CH2Cl2): ≥ 5.2 ml/g
Total swelling volume acc. Houben Weyl (in DMF): ≥ 5.1 ml/g
Identity (of the substitution): passes test
The polymer matrix is copoly (styrene-1 % DVB), 200 -400 mesh.
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.40 - 0.80 mmol/g
TNBS-Test: passes test
Swelling Volume (in DMF): lot specific result
Swelling Volume (in CH₂Cl₂): lot specific result
Total swelling volume acc. Houben Weyl (in CH2Cl2): ≥ 5.2 ml/g
Total swelling volume acc. Houben Weyl (in DMF): ≥ 5.1 ml/g
Identity (of the substitution): passes test
The polymer matrix is copoly (styrene-1 % DVB), 200 -400 mesh.
法的情報
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
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保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
資料
Novabiochem® has one of the most extensive ranges of linkers and derivatized resins for Fmoc solid phase peptide synthesis. These resins have varied properties with special protocols for loading and cleaving.
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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