8.53074

Boc-Asn(Trt)-OH

Novabiochem^®

• 別名: Boc-Asn(Trt)-OH, N-α-t.-Boc-β-trityl-L-asparagine
• 実験式（ヒル表記法）: C₂₈H₃₀N₂O₅
• CAS番号: 132388-68-2
• 分子量: 474.55
• MDL番号: MFCD00153299
• UNSPSCコード: 12352209
• NACRES: NA.22

特性

• 品質水準: 200
• 製品種目: Novabiochem^®
• アッセイ: ≥98% (TLC)
• フォーム: powder
• 反応適合性: reaction type: Boc solid-phase peptide synthesis
• メーカー／製品名: Novabiochem^®
• アプリケーション: peptide synthesis
• 官能基: amide
• 保管温度: 15-25°C
• InChI: 1S/C28H30N2O5/c1-27(2,3)35-26(34)29-23(25(32)33)19-24(31)30-28(20-13-7-4-8-14-20,21-15-9-5-10-16-21)22-17-11-6-12-18-22/h4-18,23H,19H2,1-3H3,(H,29,34)(H,30,31)(H,32,33)/t23-/m0/s1
• InChI Key: PYGOCFDOBSXROC-QHCPKHFHSA-N

詳細

詳細

A trityl-protected derivative which increases the solubility of Asn during the coupling step in SPPS ^[1]. Its use gives higher yields and lower by-product formation. During the following coupling cycles the temporary side-chain protection is removed.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Boc SPPS

Literature references

^[1] P. Sieber, et al. (1991) Tetrahedron Lett., 32, 739.

関連事項

Replaces: 04-12-0187

アナリシスノート

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in methanol): -21.5 - -16.5 °
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Solubility (1 mmole in 2 ml DMF): clear solution

To see the solvent systems used for TLC of Novabiochem^® products please click here.

法的情報

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable