8.52401

Fmoc-Asp(OEpe)-OH

Novabiochem^®

• 別名: Fmoc-Asp(OEpe)-OH, N-α-Fmoc-(O-3-ethyl-pent-3-yl)aspartic acid
• 実験式（ヒル表記法）: C₂₆H₃₁NO₆
• 分子量: 453.53
• UNSPSCコード: 12352209
• NACRES: NA.22

特性

• 品質水準: 200
• 製品種目: Novabiochem^®
• フォーム: powder
• 反応適合性: reaction type: Fmoc solid-phase peptide synthesis
• メーカー／製品名: Novabiochem^®
• アプリケーション: peptide synthesis
• 官能基: carboxylic acid
• 保管温度: 15-25°C

詳細

詳細

An excellent derivative for minimizing aspartimide formation during Fmoc SPPS of Asp-containing peptides. The bulky OEpe protecting group offers considerably more protection against the formation of aspartimide-related by-products than the commonly used OtBu and OMpe group. The combination of Asp(OEpe) and the use of 1 M Oxyma Pure in DMF for Fmoc removal results in minimal aspartimde formation.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Overcoming Aspartimide Formation in Fmoc SPPS

アナリシスノート

Colour (visual): white to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (DC (018A)): ≥ 95 %
Enantiomeric purity: ≥ 99.5 % (a/a)
Assay (HPLC, area%): ≥ 97.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem^® products please click here.

法的情報

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable