8.51061

2-Chlorotrityl chloride

Novabiochem^®

• 別名: 2-Chlorotrityl chloride
• 実験式（ヒル表記法）: C₁₉H₁₄Cl₂
• CAS番号: 42074-68-0
• 分子量: 313.22
• MDL番号: MFCD00040399
• UNSPSCコード: 12352107
• EC Index Number: 255-647-3
• NACRES: NA.22

特性

• 品質水準: 200
• 製品種目: Novabiochem^®
• アッセイ: ≥95.0% (HPLC)
• フォーム: powder
• メーカー／製品名: Novabiochem^®
• mp: 133.0-137.0 °C
• アプリケーション: peptide synthesis
• 保管温度: 2-30°C
• InChI: 1S/C19H14Cl2/c20-18-14-8-7-13-17(18)19(21,15-9-3-1-4-10-15)16-11-5-2-6-12-16/h1-14H
• InChI Key: JFLSOKIMYBSASW-UHFFFAOYSA-N

詳細

詳細

Hyperacid-labile ester protecting group ^[1]. Introduced under extremely mild conditions by reacting together the acid, trityl chloride and DIPEA in DCM. Ideal for the protection of the C-terminal carboxylic acid group of C-terminal protected peptide fragments, monoprotection of diacids and as a general carboxylic acid protecting group in organic synthesis.


Associated Protocols and Technical Articles
Guide to Selection of Orthogonally-Protected Building Blocks for Fmoc SPPS

Literature references

^[1] P. Athanassopoulos, et al. (1995) Tetrahedron Lett., 36, 5645.

関連事項

Replaces: 01-63-0045

アナリシスノート

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Melting range (lower value): ≥ 133 °C
Melting range (upper value): ≤ 137 °C
Assay (HPLC, area%): ≥ 95.0 % (a/a)

法的情報

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS05,GHS07
• シグナルワード: Warning
• 危険有害性情報: H290 - H315 - H319 - H335
• 注意書き: P234 - P261 - P264 - P271 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 8A - Combustible, corrosive hazardous materials
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable