605197

Thrombin-Activatable Fibrinolysis Inhibitor, Human

The Thrombin-Activatable Fibrinolysis Inhibitor, Human controls the biological activity of Thrombin-Activatable Fibrinolysis. This small molecule/inhibitor is primarily used for Biochemicals applications.

• 別名: Plasma Procarboxypeptidase B, TAFI
• UNSPSCコード: 12352202
• NACRES: NA.25

特性

• 品質水準: 100
• アッセイ: ≥95% (SDS-PAGE)
• 形状: liquid
• 比活性: 2-9 units/mg protein
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 輸送温度: wet ice
• 保管温度: −70°C

詳細

詳細

Native thrombin-activatable fibrinolysis inhibitor from human liver. Single chain glycoprotein synthesized in the liver. ctivated by the thrombin/thrombomodulin complex by proteolytic cleavage at Arg⁹². Circulates in plasma as a zymogen at a concentration of about 50 nM. Believed to play an important role in the interaction between procoagulant, anticoagulant, and fibrinolytic systems.

Native thrombin-activatable fibrinolysis inhibitor from human liver. Single chain glycoprotein synthesized in the liver. Circulates in plasma as a zymogen at a concentration of 50 nM. Activated by thrombin-thrombomodulin complex by proteolytic cleavage at Arg⁹². Believed to play an important role in interaction between the procoagulant, anticoagulant, and fibrinolytic systems.

包装

Please refer to vial label for lot-specific concentration.

警告

Toxicity: Standard Handling (A)

単位の定義

One unit is defined as the amount of enzyme that will hydrolyze 1 µM Hip-L-Arg per min at 25°C, pH 7.65.

物理的形状

In 150 mM NaCl, 20 mM HEPES, pH 7.4.

調製ノート

Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

再構成

Following initial thaw, aliquot and freeze (-70°C).

その他情報

Boffa, M.B., et al. 1999. Biochemistry 38, 6547.
Boffa, M.B., et al. 1998. J. Biol. Chem. 273, 2127.
Bajzar, L., et al. 1995. J. Biol. Chem. 270, 14477.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable