5.04820

Cinnabarinic acid

• 別名: Cinnabarinic acid, 2-Amino-3-oxo-3H-phenoxazine-1,9-di­carboxylic acid
• 実験式（ヒル表記法）: C₁₄H₈N₂O₆
• CAS番号: 606-59-7
• 分子量: 300.22
• MDL番号: MFCD18379297
• UNSPSCコード: 12352106
• NACRES: NA.77

特性

• アッセイ: ≥98% (HPLC)
• 品質水準: 100
• 形状: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; protect from light
• 色: red
• 溶解性: DMSO: 25 mM
• 保管温度: −20°C
• InChI: 1S/C14H8N2O6/c15-10-6(17)4-8-12(9(10)14(20)21)16-11-5(13(18)19)2-1-3-7(11)22-8/h1-4H,15H2,(H,18,19)(H,20,21)
• InChI Key: FSBKJYLVDRVPTK-UHFFFAOYSA-N

詳細

詳細

A partial, low-potency agonist highly selective for mGlu₄ receptors (EC₅₀ >100 µM, no effect on other mGlu subtype receptors). Used in assessing the functional roles of mGlu₄ receptors in a variety of research areas, such as excitotoxic cell death, apoptosis, neuroinflammation, inflammation, and neuroimmune communication.

生物化学的／生理学的作用

Primary Target
mGlu₄ receptors

警告

Toxicity: Standard Handling (A)

調製ノート

Slight warming is required for complete solubilization.

再構成

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

その他情報

Fazio, Francesco, et al. 2012. Mol. Pharmacol.81, 643.

Volpi, C., et al. 2012. Neuropharmacol.63, 501.
Hiramatsu, R., et al. 2008. J. Cell Biochem.103, 42.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable