454575

N-Methyl-D-aspartic Acid hydrate

>95% (TLC), solid, excitatory amino acid neurotransmitter, Calbiochem^®

• 別名: N-Methyl-D-aspartic Acid, Hydrate, NMDA
• 実験式（ヒル表記法）: C₅H₉NO₄ · xH₂O
• CAS番号: 6384-92-5
• 分子量: 147.13 (anhydrous basis)
• MDL番号: MFCD00004226
• UNSPSCコード: 12352209
• NACRES: NA.77

特性

• product name: N-Methyl-D-aspartic Acid, Hydrate, Excitatory amino acid neurotransmitter.
• 品質水準: 100
• アッセイ: >95% (TLC)
• 形状: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 色: white
• 溶解性: water: 1 mg/mL
• 輸送温度: ambient
• 保管温度: 10-30°C
• InChI: 1S/C5H9NO4/c1-6-3(5(9)10)2-4(7)8/h3,6H,2H2,1H3,(H,7,8)(H,9,10)/p-1/t3-/m1/s1
• InChI Key: HOKKHZGPKSLGJE-GSVOUGTGSA-M

詳細

詳細

An excitatory amino acid neurotransmitter. Selective agonist of the glutamate receptor that regulates Ca²⁺ channels. Important in long-term potentiation, ischemia, and epilepsy. NMDA receptors are involved in the "fine tuning" of synaptic connections in the developing brain. Chronic treatment with NMDA produces structural changes in synaptic morphology. Over-excitation of NMDA receptors causes neuronal degeneration and cell death.

Excitatory amino acid neurotransmitter. Selective agonist of the glutamate receptor that regulates Ca²⁺ channels. Important in long-term potentiation, ischemia, and epilepsy. NMDA receptors are involved in the "fine tuning" of synaptic connections in the developing brain. Chronic treatment with NMDA produces structural changes in synaptic morphology. Over-excitation of NMDA receptors causes neuronal degeneration and cell death.

生物化学的／生理学的作用

Cell permeable: no

Primary Target
Glutamate receptor that regulates Ca2+ channels

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Standard Handling (A)

再構成

Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for several days at 4°C.

その他情報

Mattson, M.P., et al. 1993. J. Neurosci. 13, 4575.
Yen, L-H., et al. 1993. J. Neurosci. 13, 4949.
Swann, J.W., et al. 1992. Epilepsy Res. Suppl. 9, 115.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable