407245

Insulin-Like Growth Factor-II, Human, Recombinant, E. coli

• 別名: Insulin-Like Growth Factor-II, Human, Recombinant, E. coli, rhIGF-II
• CAS番号: 67763-97-7
• UNSPSCコード: 12352202

特性

• アッセイ: ≥97% (SDS-PAGE)
• 品質水準: 100
• フォーム: lyophilized
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 不純物: <1 EU/μg Endotoxin (EU/μg IGF-II)
• 輸送温度: ambient
• 保管温度: −20°C

詳細

詳細

Recombinant, human insulin-like growth factor-II expressed in E. coli. A growth-promoting peptide that is structurally related to insulin. IGF-II shares about 76% sequence identity with IGF-I and ~50% with pro-insulin. Its actions are similar to IGF-I (Cat. No. 407240). IGF-II is a nonglycosylated, single chain peptide of 67 amino acids. Plays an important role in fetal development. Stimulates muscle and bone cell proliferation and differentiation.

Recombinant, human insulin-like growth factor-II expressed in E. coli. Its actions are similar to IGF-1 (Cat. No. 407240). Plays an important role in fetal development. Stimulates muscle and bone cell proliferation and differentiation.

生物化学的／生理学的作用

ED₅₀ = 5-10 ng/ml

警告

Toxicity: Standard Handling (A)

物理的形状

Lyophilized from sterile-filtered acetic acid.

再構成

Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 3 months at -70°C.

Reconstitute to a concentration of ≥10 µg/ml with sterile PBS containing ≥0.1% HSA or BSA. Avoid using buffers near the isoelectric point (6.5).

その他情報

Feldser, D., et al. 1999. Cancer Res.59, 3915.
Hill, P.A., et al. 1995. Endocrinology136, 124.
Nielson, F.C., et al. 1995. Nature 377, 358.
LeRoith, D., and Roberts, C.R., Jr. 1993. Ann. N.Y. Acad. Sci.692, 1.
Lowe, W.L. 1991. In Insulin-Like Growth Factors: Molecular and Cellular Aspects (LeRoith, D., Ed.) CRC Press Inc., Boca Raton p. 49.
Rotwein, P. 1991. Growth Factors5, 3.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1