345832

Galectin-3C, Human, Recombinant, E. coli

• UNSPSCコード: 12352202
• NACRES: NA.77

特性

• アッセイ: ≥95% (SDS-PAGE)
• 品質水準: 100
• 形状: lyophilized
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; avoid repeated freeze/thaw cycles
• 不純物: ≤1 EU/μg protein Endotoxin
• 溶解性: sterile PBS: 1 mg/mL
• 輸送温度: wet ice
• 保管温度: −20°C

詳細

詳細

Recombinant, human galectin-3 expressed in E. coli and subsequently cleaved with Clostridium histiolyticum collagenase type VII to yield galectin-3C. The resulting galectin-3C is purified by affinity chromatography. Galectin-3C is a truncated form of galectin-3 that contains the carbohydrate binding domain but lacks the 107 amino acids at the N-terminus of galectin-3. It is suggested to play a key role in autoimmune diseases, allergic reactions, inflammation, tumor cell metastasis, atherosclerosis, and diabetes.

Recombinant, human galectin-3 expressed in E. coli and subsequently cleaved with Clostridium histolyticum collagenase type VII to yield galectin-3C. The resulting galectin-3C is purified by affinity chromatography. Galectin-3C is a truncated form of galectin-3 that contains the carbohydrate binding domain but lacks the 107 amino acids at the N-terminus of galectin-3. It is suggested to play a key role in autoimmune diseases, allergic reactions, inflammation, tumor cell metastasis, atherosclerosis, and diabetes.

警告

Toxicity: Standard Handling (A)

物理的形状

Lyophilized from deionized water, 2µg lactose/µg lectin.

再構成

Following reconstitution, aliquot and freeze (-20°C). Stock solutions (in the presence of a molar excess of lactose) are stable for up to 4 months at -20°C. For use in carbohydrate binding assays the solution should be dialyzed to remove the lactose stabilizer.

その他情報

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Iurisci, I., et al. 2000. Clin Cancer Res6, 1389.
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Idikio, H., et al. 1998. Int. J. Oncol.12, 1287.
Ochieng, J., et al. 1998. Biochim. Biophys. Acta.1379 97.
Castronovo, V., et al. 1996. J. Pathol.179, 43.
Liu, F.T., et al. 1996. Biochemistry35 6073.
Schoeppner, H. L., et al. 1995. Cancer75, 2818.
Massa, S.M., et al. 1993. Biochemistry32, 260.
Oda, Y., et al. 1991. Gene99, 279.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable