14-720-M

FAK Protein, active, 10 µg

Active, N-terminal 6His-tagged, recombinant, human FAK, amino acids 411-686, for use in Kinase Assays.

• UNSPSCコード: 12352200
• eCl@ss: 32160405
• NACRES: NA.32

特性

• 由来生物: human
• 品質水準: 100
• リコンビナント: expressed in baculovirus infected Sf21 cells
• 製品種目: Upstate^®
• 比活性: (For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.)
• 分子量: M_w 35.5 kDa
• 精製方法: (Ni²⁺/NTA-agarose)
• 化学種の反応性: human
• メーカー／製品名: Upstate^®
• テクニック: activity assay: suitable (kinase)
• アクセッション番号: (FUNCTION: SwissProt: Q05397 # Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. ); NM_005607.3
• NCBIアクセッション番号: NM_005607.3; NM_153831.2
• UniProtアクセッション番号: Q05397
• 関連疾患: obesity; metabolic disorders
• 遺伝子情報: human ... PTK2(5747)

詳細

詳細

N-terminal 6His-tagged, recombinant, human FAK, amino acids 411-686

生物化学的／生理学的作用

Protein Target: FAK

包装

Also available in 10 μg size and in bulk

品質

100 μMの基質ペプチド(EEEEYEEEEEEYYIIEEEEEEYEEEEEEYYEEEEEEKKK)のリン酸化により定期的に評価しています。

routinely evaluated by phosphorylation of 100μM substrate peptide (EEEEYEEEEEEYYIIEEEEEEYEEEEEEYYEEEEEEKKK)

ターゲットの説明

FAK

その他情報

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法的情報

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H317
• 注意書き: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• 危険有害性の分類: Skin Sens. 1
• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(℃): Not applicable