14-440-M

PKA Protein, Recombinant, 10 µg

Recombinant human full length PKA, catalytic subunit type alpha, untagged, for use in Kinase Assays.

• UNSPSCコード: 12352202
• eCl@ss: 32160405
• NACRES: NA.41

特性

• 由来生物: human
• 品質水準: 100
• リコンビナント: expressed in E. coli; expressed in BL21 DE3 cells
• 製品種目: Upstate^®
• 形状: liquid
• 比活性: (For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.); 8580 U/mg
• シェルフライフ: 1 yr
• 分子量: M_w 40.7 kDa
• 精製方法: chromatography
• 化学種の反応性: human
• メーカー／製品名: Upstate^®
• テクニック: activity assay: suitable (kinase)
• 溶解性: water: soluble
• アクセッション番号: (FUNCTION: SwissProt: P17612 # Phosphorylates a large number of substrates in the cytoplasm and the nucleus. ); NM_002730.3
• NCBIアクセッション番号: NM_002730.3; NM_207518.1
• UniProtアクセッション番号: P17612
• 保管温度: −70°C
• 遺伝子情報: human ... PRKACA(46909581)

詳細

詳細

Research area: Cell Signaling

Product Source: Expressed in E.coli BL21 (DE3) pLysS cells Recombinant human full length PKA, catalytic subunit type alpha, untagged Protein kinase A (PKA) is a serine protein kinase and heterotetrameric holoenzyme that targets serine and threonine residues.

Recombinant human full length PKA, catalytic subunit type alpha, untagged

生物化学的／生理学的作用

Protein Target: PKA; Target Sub-Family: AGC. Protein kinases are vital for integrating signaling networks within eukaryotic cells. In Hedgehog-responsive cells, PKA is crucial for regulating proliferation and fate determination by influencing Hedgehog signaling transduction. PKA has numerous targets that are linked to adhesion or migration.

包装

Also available in 10 μg size and in bulk

Also available in 250 µg size --call for pricing and availability and reference catalog number 14-440M when ordering the 250 µg size.

品質

routinely evaluated by phosphorylation of Kemptide substrate in vitro

ターゲットの説明

PKA

関連事項

Replaces: 14-114

物理的形状

Phosphocellulose P11 chromatography

保管および安定性

1 year at -70°C

その他情報

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法的情報

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1