1.04672

コレステロール

EMPROVE^® EXPERT, Ph. Eur., BP, JP, NF

• 別名: 3β-ヒドロキシ-5-コレステン, 5-コレステン-3β-オール
• 実験式（ヒル表記法）: C₂₇H₄₆O
• CAS番号: 57-88-5
• 分子量: 386.65
• Beilstein: 1915888
• MDL番号: MFCD00003646
• UNSPSCコード: 12352104

特性

• 由来生物: synthetic
• 品質水準: 500
• 認証: BP; JP; NF; Ph. Eur.
• 製品種目: EMPROVE^® EXPERT
• 形状: powder
• bp: 360 °C (lit.)
• mp: ~141 °C; 147-149 °C (lit.)
• 密度: 1.067 g/mL at 25 °C (lit.)
• 適合性: suitable for (Suitable for formulation and manufacturing use)
• アプリケーション: advanced drug delivery; controlled release; liquid formulation; parenterals; pharmaceutical
• 保管温度: 15-25°C
• SMILES記法: CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
• InChI: 1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
• InChI Key: HVYWMOMLDIMFJA-DPAQBDIFSA-N

詳細

詳細

A GMP-scalable process which yields a high-quality lipid is essential to lipidic drug product development and manufacturing. We are highly specialized in synthesizing top-quality GMP lipids for pharmaceutical applications and gene therapy, focusing on tailored manufacturing to meet your specific needs. We also offer an off-the-shelf catalog with optimized stability, solubility, and handling characteristics.
Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

アプリケーション

Cholesterol is a major component of all biological cell membranes and is used as a stabilizer of lipid bilayers in many lipid-based formulations for the delivery of different APIs, such as small molecules and nucleic acids.
Synthetic cholesterol, Ph Eur, BP, JP, NF is ultra-pure and therefore suitable for divers formulations applications. Due to low batch to batch variability, very high purity, and lack of biological components, this product is optimal for highly sensitive applications such as nucleic acid delivery.
With a newly optimized manufacturing process, this product is available in quantities from grams to tons to support your development progress. A dual sourcing option is also possible.

生物化学的／生理学的作用

すべての生体膜の主成分。脳脂質全体の約25%はコレステロ-ルです。

法的情報

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

SyntheChol is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

The substance 1.04672 has no REACH registration because the only supported use is the use in medicinal products for human or veterinary use or in food or feedingstuffs according to article 2 of the REACH Regulation (EC) No 1907/2006.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable