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特異性
Bcl-2
免疫原
KLH-conjugated, synthetic peptide corresponding to amino acids 41-54 (C-GAAPAPGIFSSQPG) of human Bcl-2
アプリケーション
Research Category
アポトーシス及び癌
アポトーシス及び癌
Research Sub Category
BCL2とその阻害
BCL2とその阻害
This Anti-Bcl-2 Antibody, clone AW604 is validated for use in IP, WB for the detection of Bcl-2.
品質
routinely evaluated by immunoblot on Raji RIPA cell lysate
ターゲットの説明
26kDa
関連事項
Replaces: 04-436; OP60-100UG
物理的形状
Protein G Purified
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
保管および安定性
2 years at -20°C
法的情報
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
12 - Non Combustible Liquids
WGK
WGK 2
引火点(°F)
Not applicable
引火点(℃)
Not applicable
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Programmed cell death: apoptosis and oncogenesis.
Williams, G T
Cell, 65, 1097-1098 (1991)
S Krajewski et al.
Cancer research, 53(19), 4701-4714 (1993-10-01)
A multidisciplinary approach was taken to investigate the intracellular locations of the 26-kDa integral membrane protein encoded by the bcl-2 gene. Subcellular fractionation analysis of a t(14;18)-containing lymphoma cell line revealed the presence of Bcl-2 protein in nuclear, heavy-membrane, and
Differential expression of bcl2 protooncogene in neuroblastoma and other human tumor cell lines of neural origin
Reed, J C, et al
Cancer Research, 51, 6529-6538 (1991)
Ekaterina Kim et al.
Leukemia, 34(6), 1588-1598 (2019-12-22)
Despite major improvements in treatment outcome with novel targeted therapies, such as the Bruton tyrosine kinase (BTK) inhibitor ibrutinib, chronic lymphocytic leukemia (CLL) remains incurable in the majority of patients. Activation of PI3K, NF-κB, and/or MYC has been linked to
Vincenza Simona Delvecchio et al.
British journal of haematology, 189(3), 475-488 (2020-02-15)
Chronic lymphocytic leukaemia (CLL) cells are strongly influenced by microenvironmental signals through the activation of distinct membrane receptors including the B-cell receptor and toll-like receptors (TLR). Recapitulating TLR stimulation in vitro by treating CLL cells with the TLR9 ligand CpG
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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