おすすめの製品
由来生物
mouse
品質水準
抗体製品の状態
purified immunoglobulin
抗体製品タイプ
primary antibodies
クローン
2D3, monoclonal
化学種の反応性
human, mouse, rat
メーカー/製品名
Upstate®
テクニック
electrophoretic mobility shift assay: suitable
western blot: suitable
アイソタイプ
IgG1κ
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
ターゲットの翻訳後修飾
phosphorylation (pSer9)
遺伝子情報
human ... GSK3B(2932)
特異性
GSK3beta
免疫原
peptide corresponding to amino acids 6-12 (RTT[pS]AE) of human GSK3beta
アプリケーション
Research Category
細胞シグナル伝達
細胞シグナル伝達
Research Sub Category
PI3K、Akt及びmTORシグナル伝達
PI3K、Akt及びmTORシグナル伝達
Anti-phospho-GSK3β (Ser9) Antibody, clone 2D3 is an antibody against phospho-GSK3β (Ser9) for use in EMSA & WB.
品質
routinely evaluated by immunoblot on L6 cells stimulated with IGF-1
ターゲットの説明
46kDa (GSK3β) and 51kDa (GSK3α)
関連事項
Replaces: 04-1075
物理的形状
Thiophilic adsorption chromatography
100µg of thiophilic and size exclusion chromatography purified mouse IgG1κ in 100µL of antibody storage buffer (PBS with PEG, Sucrose, and 0.09% sodium azide) and 50% glycerol.
Format: Purified
保管および安定性
2 years at -20°C
法的情報
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
試験成績書(COA)
製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
International journal of medical sciences, 10(6), 782-789 (2013-05-01)
We previously reported that the constitutional flavonoid glycosides derived from herb Epimedium (EF, composed of seven flavonoid compounds with common nuclear stem) exerted beneficial effects on the bone, including promoting bone formation and inhibiting bone marrow fat deposition. Recent in
Inhibition of cyclin-dependent kinase 5 but not of glycogen synthase kinase 3-? prevents neurite retraction and tau hyperphosphorylation caused by secretable products of human T-cell leukemia virus type I-infected lymphocytes.
Journal of Neuroscience Research null
Biomedicines, 9(11) (2021-11-28)
Traumatic brain injury confers a significant and growing public health burden. It is a major environmental risk factor for dementia. Nonetheless, the mechanism by which primary mechanical injury leads to neurodegeneration and an increased risk of dementia-related diseases is unclear.
Journal of clinical medicine, 7(10) (2018-10-12)
Recent studies have indicated that several anti-hypertensive drugs may delay the development and progression of Alzheimer's disease (AD). However, the relationships among AD, hypertension, and oxidative stress remain to be elucidated. Here, we aimed to determine whether reactive oxygen species
Methods in molecular biology (Clifton, N.J.), 468, 45-65 (2008-12-23)
Glycogen synthase kinase (GSK)-3 is a key signalling intermediate in the action ofWnts. This protein kinase is ubiquitously expressed and has high inherent activity but is inhibited by activation of Wnt signalling or activation of growth factor receptor tyrosine kinases
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