05-23-3831

BQ-123, Sodium Salt

A highly potent, selective, and competitive ETA (endothelin) receptor antagonist (K_i = 40 nM for ETA versus K_i = 2.5 µM for ETB).

• 別名: BQ-123, Sodium Salt
• 実験式（ヒル表記法）: C₃₁H₄₁N₆O₇ · Na
• 分子量: 632.68
• UNSPSCコード: 12352200

特性

• 品質水準: 100
• アッセイ: ≥95% (HPLC)
• 形状: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; desiccated (hygroscopic)
• 色: white
• 溶解性: water: 1 mg/mL
• 輸送温度: ambient
• 保管温度: −20°C

詳細

詳細

A highly potent and selective ET_A (endothelin) receptor antagonist (K_i = 40 nM for ET_A versus 2.5 µM for ET_B).

A highly potent, selective, and competitive ET_A (endothelin) receptor antagonist (K_i = 40 nM for ET_A versus K_i = 2.5 μM for ET_B).

生物化学的／生理学的作用

Cell permeable: no

Primary Target
ETA (endothelin) receptor antagonist

Product does not compete with ATP.

Reversible: no

Target K_i: 40 nM for ETA versus 2.5 µM for ETB

包装

Yes

警告

Toxicity: Standard Handling (A)

シーケンス

Cyclo(D-Asp-Pro-D-Val-Leu-D-Trp, Na)

物理的形状

Supplied as a sodium salt. Sold on the basis of peptide content.

その他情報

Nambi, P., et al. 1996. J. Pharmacol. Exp. Ther.277, 1567.
Bax, W.A., and Saxena, P.R. 1994. Trends Pharmacol. Sci. 15, 379.
Ihara, M., et al. 1991. Biochem. Biophys. Res. Commun. 178, 132.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable