850376P

18:1 (Δ9-Trans) PC

1,2-dielaidoyl-sn-glycero-3-phosphocholine, powder

• 別名: 1,2-di-(9E-octadecenoyl)-sn-glycero-3-phosphocholine; PC(18:1(9E)/18:1(9E))
• 実験式（ヒル表記法）: C₄₄H₈₄NO₈P
• CAS番号: 56782-46-8
• 分子量: 786.11
• MDL番号: MFCD00065534
• UNSPSCコード: 51191904
• NACRES: NA.25

特性

• アッセイ: >99% (TLC)
• フォーム: powder
• 包装: pkg of 2 × 100 mg (850376P-200mg); pkg of 1 × 25 mg (850376P-25mg)
• メーカー／製品名: Avanti Research^™ - A Croda Brand 850376P
• 脂質タイプ: phospholipids; cardiolipins
• 輸送温度: dry ice
• 保管温度: −20°C
• SMILES記法: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C/CCCCCCCC)=O)COC(CCCCCCC/C=C/CCCCCCCC)=O)=O
• InChI: 1S/C44H84NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h20-23,42H,6-19,24-41H2,1-5H3/b22-20+,23-21+
• InChI Key: SNKAWJBJQDLSFF-DQPVQCHKSA-N

詳細

詳細

18:1 (Δ9-Trans) PC (1,2-dielaidoyl-sn-glycero-3-phosphocholine) is a lipid derivative having a phosphocholine backbone. It also has two 18 carbon fatty acid chains, each having one trans double bond at the 9th carbon. It is an isomeric glycerophosphocholine.

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

アプリケーション

18:1 (Δ9-Trans) PC (1,2-dielaidoyl-sn-glycero-3-phosphocholine) may be used:

• in the preparation of liposomes/vesicles to examine peptide-mediated leakage
• as a standard phospholipid and a model compound to study the effect of several matrix-assisted laser desorption/ionization (MALDI) matrixes on the degree of the fragmentation of different phospholipids
• as a phosphatidylcholine standard to demonstrate the analytical utility of performing ozonolysis (LC-Oz-IM-MS)

生物化学的／生理学的作用

18:1 (Δ9-Trans) PC (1,2-dielaidoyl-sn-glycero-3-phosphocholine) can help paclitaxel in forming thermodynamically stable systems. It has efficient drug penetration ability into the lipid monolayers when compared to other lipids.

包装

5 mL Clear Glass Sealed Ampule (850376P-200mg)

5 mL Clear Glass Sealed Ampule (850376P-25mg)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H315,H319,H335
• 注意書き: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable