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アッセイ
>99% (TLC)
形状
powder
包装
pkg of 1 × 1 mg (810122P-1mg)
pkg of 5 × 1 mg (810122P-5mg)
メーカー／製品名
Avanti Research™ - A Croda Brand 810122P
輸送温度
dry ice
保管温度
−20°C
詳細
Phosphatidylcholine (PC) is the most abundant phospholipid in eukaryotes and prime metabolite of glycerolipid metabolism. It is a vital component of the mucosal layer of the colon. NBD PC is a fluorophore with 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) labeled to the phosphatidylcholine.
アプリケーション
14:0-06:0 NBD PC may be used as a fluorescent marker in the preparation of hyaluronan (HA)-phospholipid medium for tribological studies against live cartilage. It might also be used as a substrate for type IV P-type ATPases (P4-ATPases), in the directed evolution approach to examine the molecular mechanisms of substrate backbone discrimination.
生物化学的／生理学的作用
7-nitrobenz-2-oxa-1,3-diazol-4-yl phosphatidylcholine (NBD PC) functions as a fluorescent lipid analog, used in biological membranes to study various cellular processes. It plays a vital role as a strong bilayer-forming lipid.
包装
5 mL Amber Glass Screw Cap Vial (810122P-1mg)
5 mL Amber Glass Screw Cap Vial (810122P-5mg)
法的情報
Avanti Research is a trademark of Avanti Polar Lipids, LLC
保管分類コード
11 - Combustible Solids
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
810122P-5MG:
810122P-BULK:
810122P-1MG:
810122P-VAR:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Teresa Veselack et al.
Lubricants (Basel, Switzerland), 6(1) (2018-03-13)
Pre-clinical testing of hemiarthroplasty devices requires that the tribological conditions present in vivo with live cartilage be closely duplicated. A current limitation in the tribological testing of live cartilage involves the use of cell-culture media as lubricant. to develop and
Bartholomew P Roland et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(31), E4460-E4466 (2016-07-20)
Phospholipid flippases in the type IV P-type ATPase (P4-ATPases) family establish membrane asymmetry and play critical roles in vesicular transport, cell polarity, signal transduction, and neurologic development. All characterized P4-ATPases flip glycerophospholipids across the bilayer to the cytosolic leaflet of
Yi-Chih Lin et al.
Nature communications, 11(1), 230-230 (2020-01-15)
Annexins are abundant cytoplasmic proteins, which bind to membranes that expose negatively charged phospholipids in a Ca2+-dependent manner. During cell injuries, the entry of extracellular Ca2+ activates the annexin membrane-binding ability, subsequently initiating membrane repair processes. However, the mechanistic action of
Wei Zong et al.
Langmuir : the ACS journal of surfaces and colloids, 34(23), 6874-6886 (2018-05-20)
The success of nanoparticulate formulations in drug delivery depends on various aspects including their toxicity, internalization, and intracellular location. Vesicular assemblies consisting of phospholipids and amphiphilic block copolymers are an emerging platform, which combines the benefits from liposomes and polymersomes
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