700070P

trihydroxycholestanoic acid

Avanti Research^™ - A Croda Brand

• 別名: 3α,7α,12α-trihydroxycholestanoic acid
• 実験式（ヒル表記法）: C₂₇H₄₆O₅
• CAS番号: 547-98-8
• 分子量: 450.65
• MDL番号: MFCD23103336
• UNSPSCコード: 12352211
• NACRES: NA.25

特性

• アッセイ: >99% (TLC)
• フォーム: powder
• 包装: pkg of 1 × 1 mg (700070P-1mg)
• メーカー／製品名: Avanti Research^™ - A Croda Brand
• 脂質タイプ: bile acids
• 輸送温度: dry ice
• 保管温度: −20°C
• SMILES記法: O[C@H]1[C@@H]2[C@@H]([C@@]4([C@H](C1)C[C@@H](CC4)O)C)C[C@@H]([C@]3([C@H]2CC[C@@H]3[C@@H](CCCC(C)C(=O)O)C)C)O
• InChI: 1S/C27H46O5/c1-15(6-5-7-16(2)25(31)32)19-8-9-20-24-21(14-23(30)27(19,20)4)26(3)11-10-18(28)12-17(26)13-22(24)29/h15-24,28-30H,5-14H2,1-4H3,(H,31,32)/t15-,16?,17+,18-,19-,20+,21+,22-,23+,24+,26+,27-/m1/s1
• InChI Key: CNWPIIOQKZNXBB-VCVMUKOKSA-N

詳細

詳細

Trihydroxycholestanoic acid (THCA) is an oxidative metabolite of cholesterol and a precursor to bile acids. Very long-chain acyl-CoA synthetase (VLCS) associated with endoplasmic reticulum and peroxisomes activates THCA, the C27 bile acid intermediate.

アプリケーション

Trihydroxycholestanoic acid has been used as a sterol to test its reactivity with human mincle protein.

生物化学的／生理学的作用

Trihydroxycholestanoic acid (THCA) and dihydroxycholestanoic (DHCA) accumulation is observed in Zellweger syndrome and cholestatic liver disease. The synthesis of (25R)-isomer of DHCA and THCA is favored by mitochondrial 27-hydroxylase.

包装

5 mL Amber Glass Screw Cap Vial (700070P-1mg)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): No data available
• 引火点(℃): No data available