937819

Methoxy-poly(ethylene glycol) amine-block-poly-L-lysine hydrobromide

PEG average M_n 2000, PLLA average M_n 5000

• 別名: Block copolymer, Drug delivery polymer, Polymeric micelles, Tissue engineering, Tumor imaging, mPEG-amine2k -PLL5k, mPEGNH₂-PLL (Hidden synonyms: Polymeric micelles, Block copolymer, Tumor imaging, Tissue engineering, Drug delivery polymer)
• 化学式: C₃H₉NO(OC₂H₄)_x-(C₆H₁₃N₂OBr)_n
• UNSPSCコード: 12162002
• NACRES: NA.21

特性

• 形状: chunks
• 品質水準: 100
• 分子量: PEG average M_n 2000; PLLA average M_n 5000
• 色: white
• 保管温度: 2-8°C
• SMILES記法: COCCOCCNC(C(CCCC[NH3+])N[H])=O.[Br-]
• InChI: 1S/C11H25N3O3.BrH/c1-16-8-9-17-7-6-14-11(15)10(13)4-2-3-5-12;/h10H,2-9,12-13H2,1H3,(H,14,15);1H

詳細

詳細

Methoxy poly(ethylene glycol) amine-block-poly(L-lysine) (mPEG-PLL) is a cationic diblock copolymer consisting of amine-functionalized PEG and PLL that can be used in drug delivery applications. The cationic PLL block can bind to DNA or RNA, as well as other therapuetic agents, while the amine-functionalized PEG block can be further functionalized with targeting moieties for targeted and controlled drug delivery. This cationic diblock copolymer can self-assemble in the presence of a drug to form polymeric micelles and polymersomes.

アプリケーション

*Non-viral gene delivery application
*Targeted drug delivery application
*Protein coatings and tissue culture

特徴および利点

*Self-assemble capability to form micelles and polymersomes
*Amine functional group at the side chain enables further rapid functionalization
*Cationic poly(L-lysine) has excellent DNA and RNA condensation property
*Biodegradable, biocompatible and water soluble

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable