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PEG-b-PMPC is a biocompatible, non-fouling block copolymer composed of a neutral PEG block and a zwitterionic poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) block.
Poly (2-Methacryloyloxyethyl phosphorylcholine) (PMPC) is a methacrylate based polymer with a zwitterionic phosphorylcholine moiety on the side chain. The phosphorylcholine moiety is very similar to the head group of phospholipids in cell membranes. Due to this unique structure, PMPC showed excellent resistance to nonspecific protein adsorption, cell adhesion, and blood coagulation, as well as cell membrane penetration and underwater lubrication.
PMPC has been widely exploited in a diverse range of applications including
Poly (2-Methacryloyloxyethyl phosphorylcholine) (PMPC) is a methacrylate based polymer with a zwitterionic phosphorylcholine moiety on the side chain. The phosphorylcholine moiety is very similar to the head group of phospholipids in cell membranes. Due to this unique structure, PMPC showed excellent resistance to nonspecific protein adsorption, cell adhesion, and blood coagulation, as well as cell membrane penetration and underwater lubrication.
PMPC has been widely exploited in a diverse range of applications including
- antifouling materials for water treatment
- bioengineering
- nanomedicine
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
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Jan Code
925632-1G:
925632-BULK:
925632-VAR:
最新バージョンのいずれかを選択してください：
An introduction to zwitterionic polymer behavior and applications in solution and at surfaces.
Blackman L D, et al.
Chemical Society Reviews, 48, 757-757 (2019)
Andrew Lewis et al.
Bioconjugate chemistry, 19(11), 2144-2155 (2008-11-01)
The water-soluble, biocompatible polymer poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) was evaluated for protein conjugation. PMPC is a zwitterionic polymer that is able to form a more compact conformation in aqueous solution than poly(ethylene glycol) (PEG). While a terminally functionalized N-hydroxysuccinimide derivative of
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