901397

Poly(ethylene glycol) linear dendrimer

NHBoc terminated, PEG M_n 6000, generation 4

• 別名: Dendron bifunctionalized PEG, PFD-G4-PEG6k-NHBoc, Polyethylene glycol
• 実験式（ヒル表記法）: C₆₇₈H₁₂₀₂N₃₂O₃₂₃
• 分子量: 14970.82
• UNSPSCコード: 51171641
• NACRES: NA.23

特性

• 品質水準: 100
• フォーム: solid
• 分子量: PEG M_n 6000
• 色: white to off-white
• 保管温度: −20°C

詳細

詳細

• Polymer architecture: Dendron-functionalized PEG
• Generation: 4
• PEG Average Mn: 6,000
• End group functionality: Boc-protected amine
• No. surface groups: 32
• Calculated mol. wt.: 14970.98 g/mol
• Boc: tert-Butyloxycarbonyl
• Bis-MPA: 2,2-bis(hydroxymethyl)propionic acid

アプリケーション

Bis-MPA (or 2,2-bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers. Dendrons synthesized from bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research applications. These materials have been used in many applications such as signal amplification in bioassays and in drug delivery applications. PEG-core dendrimers feature excellent solubility in water and a high degree of functionality per PEG chain, making them strong candidates for advanced drug delivery systems or as targeting vessels. Additionally, the terminal amine groups can readily be used in EDC or DCC coupling reactions (after Boc deprotection) with carbonyl-containing compounds, to yield highly functionalized materials for a variety of biomedical applications.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable