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詳細
Gold nanoparticles PEG 5000 biotin terminated.The preparation of biotinylated gold nanoparticles involves two surface modification steps. First the carboxyl-terminated alkanethiol is attached to the surface of gold nanoparticles via chemisorption in the presence of a stabilizing agent. This step is followed by the reaction of the carboxyl groups with (+)-biotinyl-3,6,9,-trioxaundecanediamine and 2-(2-aminoethoxy)ethanol.
アプリケーション
Biotin functionalized gold nanoparticles are suitable for binding of streptavidin labelled conjugates. The gold nanoparticle label allows for straightforward detection of streptavidin by measuring the increase in absorbance of the sample upon binding. The absorption maximum is gold nanoparticle size dependent and ranges from 515-520nm for a 5nm particle to 572nm for a 100nm particle.
Gold nanoparticles 40 nm diameter, biotin terminated, PEG 5000 coated, OD 50, dispersion in H2O can be used as a theranostic agent for potential usage in cancer therapy and treatment of COVID-19. It can also be used in the detection of pathogens for biosensing applications. AuNPs may be used to prepare SARS-CoV-2 conjugate for COVID-19 detection using lateral flow immunoassay technique.
法的情報
CytoDiagnostics社の製品です。
保管分類コード
12 - Non Combustible Liquids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
808865-VAR:
808865-0.5ML:
808865-0.5ML-PW:
808865-BULK:
Controlled and reversible aggregation of biotinylated gold nanoparticles with streptavidin.
The Journal of Physical Chemistry B, 108(40), 15631-15639 (2004)
Gold nanoparticles surface-functionalized with paclitaxel drug and biotin receptor as theranostic agents for cancer therapy
Biomaterials, 33(3), 856-866 (2012)
Optimizing use of theranostic nanoparticles as a life-saving strategy for treating COVID-19 patients
Theranostics, 10(13), 5932-5932 (2020)
Recent advances in nanoparticle-based lateral flow immunoassay as a point-of-care diagnostic tool for infectious agents and diseases
Analyst, 143(9), 1970-1996 (2018)
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