188956

4-フェニルウラゾール

98%

• 別名: 4-フェニル-1,2,4-トリアゾリジン-3,5-ジオン
• 実験式（ヒル表記法）: C₈H₇N₃O₂
• CAS番号: 15988-11-1
• 分子量: 177.16
• Beilstein: 163361
• EC Number: 240-127-0
• MDL番号: MFCD00005226
• UNSPSCコード: 12352100
• PubChem Substance ID: 24851358
• NACRES: NA.22

特性

• アッセイ: 98%
• mp: 207-209 °C (lit.)
• SMILES記法: O=C1NNC(=O)N1c2ccccc2
• InChI: 1S/C8H7N3O2/c12-7-9-10-8(13)11(7)6-4-2-1-3-5-6/h1-5H,(H,9,12)(H,10,13)
• InChI Key: GOSUFRDROXZXLN-UHFFFAOYSA-N

詳細

詳細

4-Phenylurazole undergoes oxidation in the presence of NO₂-N₂O₄ to yield 4-phenyl-1,2,4-trizoline-3,5-dione. It undergoes acetylation reaction with excess acetyl chloride in N,N-dimethylacetamide solution. It polymerizes in the presence of phosgene, terephthaloyl chloride and epichlorohydrin to yield insoluble polymer. It is precursor to the Diels-Alder trapping agent, 4-phenyl-1,2,4-triazoline-3,5-dione. This urazole was recently demonstrated in the traceless, chemoselective labeling of peptides and proteins through electrochemical tyrosine-click (e-Y-CLICK) chemistry.

その他情報

Electrochemically Promoted Tyrosine-Click-Chemistry for Protein Labeling

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)