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アッセイ
≥99.0% (NT)
形状
powder
光学活性
[α]20/D +21±2°, c = 2% in acetic acid: water (4:1) (+ 1 Eq HCl)
光学純度
enantiomeric ratio: ≥99.5:0.5 (TLC)
反応適合性
reaction type: solution phase peptide synthesis
mp
~227 °C (dec.)
アプリケーション
peptide synthesis
SMILES記法
N[C@@H](COCc1ccccc1)C(O)=O
InChI
1S/C10H13NO3/c11-9(10(12)13)7-14-6-8-4-2-1-3-5-8/h1-5,9H,6-7,11H2,(H,12,13)/t9-/m0/s1
InChI Key
IDGQXGPQOGUGIX-VIFPVBQESA-N
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保管分類コード
13 - Non Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Gloves, type N95 (US)
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
13900-25G-F:
13900-VAR-F:
13900-1G-F:
13900-BULK-F:
13900-5G-F:
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To investigate the in vitro release of octreotide acetate, a somatostatin agonist, from microspheres based on a hydrophilic polyester, poly(D,L-lactide-co-hydroxymethyl glycolide) (PLHMGA). Spherical and non-porous octreotide-loaded PLHMGA microspheres (12 to 16 μm) and loading efficiency of 60-70% were prepared by a
Amir H Ghassemi et al.
Pharmaceutical research, 27(9), 2008-2017 (2010-07-06)
To study the release of a model protein, bovine serum albumin (BSA), from microspheres of an hydroxylated aliphatic polyester, poly(lactic-co-hydroxymethyl glycolic acid) (PLHMGA). BSA-loaded microspheres were prepared by a double emulsion solvent evaporation method. The effect of copolymer composition and
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Inhibitors of cyclin-dependent kinases 4 and 6 (CDK4/6i) delay progression of metastatic breast cancer. However, complete responses are uncommon and tumors eventually relapse. Here, we show that CDK4/6i can enhance efficacy of T cell-based therapies, such as adoptive T cell transfer or
Neda Samadi et al.
Pharmaceutical research, 31(10), 2593-2604 (2014-03-15)
To investigate the effect of polyethylene glycol (PEG) in nanoparticles based on blends of hydroxylated aliphatic polyester, poly(D,L-lactic-co-glycolic-co-hydroxymethyl glycolic acid) (PLGHMGA) and PEG-PLGHMGA block copolymers on their degradation and release behavior. Protein-loaded nanoparticles were prepared with blends of varying ratios
F Kazazi-Hyseni et al.
International journal of pharmaceutics, 482(1-2), 99-109 (2014-12-17)
Poly(D,L-lactic-co-hydroxymethyl glycolic acid) (PLHMGA) is a biodegradable copolymer with potential as a novel carrier in polymeric drug delivery systems. In this study, the biocompatibility of PLHMGA microspheres (PLHMGA-ms) was investigated both in vitro in three different cell types (PK-84, HK-2
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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